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Vesicular Stomatitis Virus: From Agricultural Pathogen to Vaccine Vector

Pathogens, 2021
Vesicular stomatitis virus (VSV), which belongs to the Vesiculovirus genus of the family Rhabdoviridae, is a well studied livestock pathogen and prototypic non-segmented, negative-sense RNA virus.
Guodong Liu, Wenguang Cao, Abdjeleel Salawudeen, Wenjun Zhu, Karla Emeterio, David Safronetz, Logan Banadyga   +6 more
doaj   +5 more sources

Protective Efficacy of Lyophilized Vesicular Stomatitis Virus–Based Vaccines in Animal Model [PDF]

Emerging Infectious Diseases
We evaluated the in vitro effects of lyophilization for 2 vesicular stomatitis virus–based vaccines by using 3 stabilizing formulations and demonstrated protective immunity of lyophilized/reconstituted vaccine in guinea pigs.
Abd’jeleel Salawudeen, Geoff Soule, Nikesh Tailor, Levi Klassen, Jonathan Audet, Angela Sloan, Yvon Deschambault, David Safronetz   +7 more
doaj   +2 more sources

Vesicular Stomatitis Virus Transmission Dynamics Within Its Endemic Range in Chiapas, Mexico [PDF]

Viruses
Vesicular stomatitis virus (VSV), comprising vesicular stomatitis New Jersey virus (VSNJV) and vesicular stomatitis Indiana virus (VSIV), emerges from its focus of endemic transmission in Southern Mexico to cause sporadic livestock epizootics in the ...
Lawrence H. Zhou, Federico Valdez, Irene Lopez Gonzalez, Willian Freysser Urbina, Ariadna Ocaña, Cristell Tapia, Armando Zambrano, Edilberto Hernandez Solis, Debra P. C. Peters, Chad E. Mire, Roberto Navarro, Luis L. Rodriguez, Kathryn A. Hanley   +12 more
doaj   +2 more sources

Recombinant vesicular stomatitis virus vector vaccines for WHO blueprint priority pathogens

Human Vaccines and Immunotherapeutics, 2019
The devastating Ebola virus (EBOV) outbreak in West Africa in 2013–2016 has flagged the need for the timely development of vaccines for high-threat pathogens. To be better prepared for new epidemics, the WHO has compiled a list of priority pathogens that
Christine Dahlke, Anahita Fathi, Marylyn Addo   +2 more
exaly   +2 more sources

Vesicular Stomatitis Virus Transmission: A Comparison of Incriminated Vectors

Insects, 2018
Vesicular stomatitis (VS) is a viral disease of veterinary importance, enzootic in tropical and subtropical regions of the Americas. In the U.S., VS produces devastating economic losses, particularly in the southwestern states where the outbreaks display
Paula Rozo-Lopez, Barbara S. Drolet, Berlin Londoño-Renteria   +2 more
doaj   +2 more sources

Vesicular Stomatitis Virus.

The Veterinary clinics of North America. Food animal practice, 2022
Vesicular stomatitis (VS) is a vector-borne livestock disease caused by either VS New Jersey virus or VS Indiana virus. The disease circulates endemically in northern South America, Central America, and Mexico and only occasionally causes outbreaks in ...
A. Pelzel-McCluskey
semanticscholar   +1 more source

Review of Vesicular Stomatitis in the United States with Focus on 2019 and 2020 Outbreaks

Pathogens, 2021
Vesicular stomatitis (VS) is a vector-borne livestock disease caused by vesicular stomatitis New Jersey virus (VSNJV) or vesicular stomatitis Indiana virus (VSIV).
Angela Pelzel-McCluskey, Brad Christensen, John Humphreys, Miranda Bertram, Robert Keener, Robert Ewing, Lee W. Cohnstaedt, Rachel Tell, Debra P. C. Peters, Luis Rodriguez   +9 more
doaj   +1 more source

Molecular Tracking of the Origin of Vesicular Stomatitis Outbreaks in 2004 and 2018, Ecuador

Veterinary Sciences, 2023
The Vesicular Stomatitis Virus (VSV) is an arbovirus causing vesicular stomatitis (VS) in livestock. There are two serotypes recognized: New Jersey (VSNJV) and Indiana (VSIV). The virus can be transmitted directly by contact or by vectors.
David Vasco-Julio, Dayana Aguilar, Alexander Maldonado, Euclides de la Torre, Maria Soledad Cisneros-Montufar, Carlos Bastidas-Caldes, Juan-Carlos Navarro, Jacobus H. de Waard   +7 more
doaj   +1 more source

Effect of Recombinant Vesicular Stomatitis Virus–Zaire Ebola Virus Vaccination on Ebola Virus Disease Illness and Death, Democratic Republic of the Congo

Emerging Infectious Diseases, 2022
We conducted a retrospective cohort study to assess the effect vaccination with the live-attenuated recombinant vesicular stomatitis virus–Zaire Ebola virus vaccine had on deaths among patients who had laboratory-confirmed Ebola virus disease (EVD).
Neil Rupani, Mbong Eta Ngole, J. Austin Lee, Adam R. Aluisio, Monique Gainey, Shiromi M. Perera, Lina Kashibura Ntamwinja, Ruffin Mbusa Matafali, Rigo Fraterne Muhayangabo, Fiston Nganga Makoyi, Razia Laghari, Adam C. Levine, Alexis S. Kearney   +12 more
doaj   +1 more source

Replication-Competent Vesicular Stomatitis Virus Vaccine Vector Protects against SARS-CoV-2-Mediated Pathogenesis in Mice

Cell Host and Microbe, 2020
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused millions of human infections, and an effective vaccine is critical to mitigate coronavirus-induced disease 2019 (COVID-19). Previously, we developed a replication-competent vesicular
J. Case, Paul W. Rothlauf, Rita E. Chen, Natasha M. Kafai, J. Fox, Brittany K. Smith, S. Shrihari, Broc T. McCune, Ian B Harvey, Shamus P. Keeler, L. Bloyet, Haiyan Zhao, Meisheng Ma, L. Adams, Emma S. Winkler, M. Holtzman, D. Fremont, Sean P. J. Whelan, M. Diamond   +18 more
semanticscholar   +1 more source