Results 11 to 20 of about 40,172 (184)

A VSV-based assay quantifies coronavirus Mpro/3CLpro/Nsp5 main protease activity and chemical inhibition

open access: yesCommunications Biology, 2022
A vesicular stomatitis virus (VSV)-based assay enables high-throughput screening for small molecular protease inhibitors that can block viral proteases, like the Mpro/3CLpro/Nsp5 in SARS-CoV-2.
Emmanuel Heilmann   +7 more
doaj   +1 more source

Examination of vesicular stomatitis virus-induced morphology changes in individual Vero cells by QMod microscopy

open access: yesBioTechniques, 2020
Viral infection of cultured cells induces changes in the biophysical characteristics of the affected cells. Advanced microscopic cameras such as Ovizio’s QMod, coupled with the appropriate software, can measure a variety of characteristics on a per-cell ...
Isabel Scholz   +2 more
doaj   +1 more source

The nucleocapsid of vesicular stomatitis virus [PDF]

open access: yesScience China Life Sciences, 2012
The nucleocapsid of vesicular stomatitis virus serves as the genomic template for transcription and replication. The viral genomic RNA is sequestered in the nucleocapsid in every step of the virus replication cycle. The structure of the nucleocapsid and the entire virion revealed how the viral genomic RNA is encapsidated and packaged in the virus.
openaire   +2 more sources

Aptamer-facilitated Protection of Oncolytic Virus from Neutralizing Antibodies

open access: yesMolecular Therapy: Nucleic Acids, 2014
Oncolytic viruses promise to significantly improve current cancer treatments through their tumor-selective replication and multimodal attack against cancer cells.
Darija Muharemagic   +6 more
doaj   +1 more source

Carbohydrate Composition of Vesicular Stomatitis Virus [PDF]

open access: yesJournal of Virology, 1971
Analysis by gas-liquid chromatography of the trimethylsilylated sugar residues of purified vesicular stomatitis virus grown in L cells or chick embryo cells revealed the presence in the whole virion of four hexoses (glucose, galactose, mannose, and fucose), two hexosamines (glucosamine and galactosamine), and 34 to 40% neuraminic acid.
J J, McSharry, R R, Wagner
openaire   +2 more sources

Viroses confundíveis com febre aftosa Viral diseases to be differentiated from foot-and-mouth disease

open access: yesCiência Rural, 1996
Revisam-se as doenças que devem ser consideradas no diagnóstico diferencial de febre aftosa. Dentre as doenças vesiculares ou erosivas, descrevem-se os principais aspectos relacionados ao diagnóstico da estomatite vesicular, diarréia viral bovina, febre ...
Franklin Riet-Correa   +3 more
doaj   +1 more source

A method for the generation of pseudovirus particles bearing SARS coronavirus spike protein in high yields

open access: yesCell Structure and Function, 2022
The ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has threatened human health and the global economy. Development of additional vaccines and therapeutics is urgently required, but such development with live virus must be ...
Yoichiro Fujioka   +7 more
doaj   +1 more source

Fitness Determinations in Vesicular Stomatitis Virus

open access: yesBio-Protocol, 2014
Fitness is defined as the overall replicative ability. Testing whether a mutation (or combination of mutations) has an effect on fitness often relays on determining virus production as a surrogate measurement. However, viruses do not usually replicate in
Isabel Novella
doaj   +1 more source

Bat Employs a Conserved MDA5 Gene to Trigger Antiviral Innate Immune Responses

open access: yesFrontiers in Immunology, 2022
Bats are important hosts for various zoonotic viral diseases. However, they rarely show signs of disease infection with such viruses. As the first line for virus control, the innate immune system of bats attracted our full attention.
Jie Wang   +9 more
doaj   +1 more source

Atomic model of vesicular stomatitis virus and mechanism of assembly

open access: yesNature Communications, 2022
Zhou and Si et al. used cryogenic electron microscopy and tomography to delineate the molecular interactions among genomic RNA, nucleocapsid protein, matrix protein and glycoprotein in vesicular stomatitis virus and suggest a model of assembly.
Kang Zhou   +5 more
doaj   +1 more source

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