Results 11 to 20 of about 40,172 (184)
A vesicular stomatitis virus (VSV)-based assay enables high-throughput screening for small molecular protease inhibitors that can block viral proteases, like the Mpro/3CLpro/Nsp5 in SARS-CoV-2.
Emmanuel Heilmann +7 more
doaj +1 more source
Viral infection of cultured cells induces changes in the biophysical characteristics of the affected cells. Advanced microscopic cameras such as Ovizio’s QMod, coupled with the appropriate software, can measure a variety of characteristics on a per-cell ...
Isabel Scholz +2 more
doaj +1 more source
The nucleocapsid of vesicular stomatitis virus [PDF]
The nucleocapsid of vesicular stomatitis virus serves as the genomic template for transcription and replication. The viral genomic RNA is sequestered in the nucleocapsid in every step of the virus replication cycle. The structure of the nucleocapsid and the entire virion revealed how the viral genomic RNA is encapsidated and packaged in the virus.
openaire +2 more sources
Aptamer-facilitated Protection of Oncolytic Virus from Neutralizing Antibodies
Oncolytic viruses promise to significantly improve current cancer treatments through their tumor-selective replication and multimodal attack against cancer cells.
Darija Muharemagic +6 more
doaj +1 more source
Carbohydrate Composition of Vesicular Stomatitis Virus [PDF]
Analysis by gas-liquid chromatography of the trimethylsilylated sugar residues of purified vesicular stomatitis virus grown in L cells or chick embryo cells revealed the presence in the whole virion of four hexoses (glucose, galactose, mannose, and fucose), two hexosamines (glucosamine and galactosamine), and 34 to 40% neuraminic acid.
J J, McSharry, R R, Wagner
openaire +2 more sources
Revisam-se as doenças que devem ser consideradas no diagnóstico diferencial de febre aftosa. Dentre as doenças vesiculares ou erosivas, descrevem-se os principais aspectos relacionados ao diagnóstico da estomatite vesicular, diarréia viral bovina, febre ...
Franklin Riet-Correa +3 more
doaj +1 more source
The ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has threatened human health and the global economy. Development of additional vaccines and therapeutics is urgently required, but such development with live virus must be ...
Yoichiro Fujioka +7 more
doaj +1 more source
Fitness Determinations in Vesicular Stomatitis Virus
Fitness is defined as the overall replicative ability. Testing whether a mutation (or combination of mutations) has an effect on fitness often relays on determining virus production as a surrogate measurement. However, viruses do not usually replicate in
Isabel Novella
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Bat Employs a Conserved MDA5 Gene to Trigger Antiviral Innate Immune Responses
Bats are important hosts for various zoonotic viral diseases. However, they rarely show signs of disease infection with such viruses. As the first line for virus control, the innate immune system of bats attracted our full attention.
Jie Wang +9 more
doaj +1 more source
Atomic model of vesicular stomatitis virus and mechanism of assembly
Zhou and Si et al. used cryogenic electron microscopy and tomography to delineate the molecular interactions among genomic RNA, nucleocapsid protein, matrix protein and glycoprotein in vesicular stomatitis virus and suggest a model of assembly.
Kang Zhou +5 more
doaj +1 more source

