Results 11 to 20 of about 1,140,792 (221)

TRIM69 Inhibits Vesicular Stomatitis Indiana Virus [PDF]

Journal of Virology, 2019
Vesicular stomatitis Indiana virus (VSIV) is a veterinary pathogen that is also used as a backbone for many oncolytic and vaccine strategies. In natural and therapeutic settings, viral infections like VSIV are sensed by the host, and as a result the host
Suzannah J. Rihn, M. A. Aziz, Douglas G. Stewart, J. Hughes, Matthew L. Turnbull, M. Varela, Elena Sugrue, C. Herd, M. Stanifer, S. Sinkins, M. Palmarini, Sam J. Wilson   +11 more
semanticscholar   +2 more sources

Rapid Quantification of SARS-CoV-2-Neutralizing Antibodies Using Propagation-Defective Vesicular Stomatitis Virus Pseudotypes [PDF]

Vaccines, 2020
Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2, a new member of the genus Betacoronavirus, is a pandemic virus, which has caused numerous fatalities, particularly in the elderly and persons with underlying morbidities. At present, there
F. Zettl, T. Meister, T. Vollmer, Bastian Fischer, J. Steinmann, A. Krawczyk, P. V’kovski, D. Todt, E. Steinmann, S. Pfaender, G. Zimmer   +10 more
semanticscholar   +3 more sources

Vesicular Stomatitis Virus–Based Vaccines against Lassa and Ebola Viruses

Emerging Infectious Diseases, 2015
We demonstrated that previous vaccination with a vesicular stomatitis virus (VSV)–based Lassa virus vaccine does not alter protective efficacy of subsequent vaccination with a VSV-based Ebola virus vaccine.
Andrea Marzi, Friederike Feldmann, Thomas W. Geisbert, Heinz Feldmann, David Safronetz   +4 more
doaj   +2 more sources

A Replication-Competent Vesicular Stomatitis Virus for Studies of SARS-CoV-2 Spike-Mediated Cell Entry and Its Inhibition

Cell Host and Microbe, 2020
There is an urgent need for vaccines and therapeutics to prevent and treat COVID-19. Rapid SARS-CoV-2 countermeasure development is contingent on the availability of robust, scalable, and readily deployable surrogate viral assays to screen antiviral ...
M. Dieterle, Denise Haslwanter, R. Bortz, A. Wirchnianski, G. Lasso, O. Vergnolle, Shawn A. Abbasi, J. Fels, E. Laudermilch, Catalina Florez, Amanda Mengotto, Duncan J. Kimmel, Ryan J. Malonis, G. Georgiev, Jose A. Quiroz, Jason C. Barnhill, L. Pirofski, J. Daily, J. Dye, Jonathan R. Lai, A. Herbert, K. Chandran, R. Jangra   +22 more
semanticscholar   +1 more source

A tool with many applications: vesicular stomatitis virus in research and medicine

Expert Opinion on Biological Therapy, 2020
Introduction Vesicular stomatitis virus (VSV) has long been a useful research tool in virology and recently become an essential part of medicinal products.
Altar M. Munis, E. Bentley, Y. Takeuchi
semanticscholar   +1 more source

Integrin Alpha E (CD103) Limits Virus-Induced IFN-I Production in Conventional Dendritic Cells

Frontiers in Immunology, 2021
Early and strong production of IFN-I by dendritic cells is important to control vesicular stomatitis virus (VSV), however mechanisms which explain this cell-type specific innate immune activation remain to be defined.
Vikas Duhan, Vikas Duhan, Vishal Khairnar, Vishal Khairnar, Simo Kitanovski, Thamer A. Hamdan, Thamer A. Hamdan, Andrés D. Klein, Andrés D. Klein, Judith Lang, Murtaza Ali, Tom Adomati, Hilal Bhat, Hilal Bhat, Sarah-Kim Friedrich, Fanghui Li, Philippe Krebs, Anthony H. Futerman, Marylyn M. Addo, Marylyn M. Addo, Marylyn M. Addo, Cornelia Hardt, Daniel Hoffmann, Philipp A. Lang, Karl S. Lang   +24 more
doaj   +1 more source

CONSTRUCTION AND STUDY OF Althaea officinalis TRANSGENIC ROOTS CULTURE WITH HUMAN INTERFERON α2B GENE [PDF]

Biotechnologia Acta, 2013
The aim of our work was to obtain Althaea officinalis L. «hairy» root culture with human interferon α2b gene (ifn-α2b), to measure fructans content and antiviral activity of extracts from the transgenic roots. Transformation of leaf and root explants was
N. A. Matvieieva, Yu. I. Kudriavets, A. A. Lichova, O. Yu. Kvasko, A. M. Shachovsky   +4 more
doaj   +1 more source

Cell cycle progression or translation control is not essential for vesicular stomatitis virus oncolysis of hepatocellular carcinoma. [PDF]

, 2010
The intrinsic oncolytic specificity of vesicular stomatitis virus (VSV) is currently being exploited to develop alternative therapeutic strategies for hepatocellular carcinoma (HCC). Identifying key regulators in diverse transduction pathways that define
Enrico N. De Toni, Jennifer Altomonte, Roland M Schmid, Schneider, Günter, Schmid, Roland M., Rizzani Antonia, Thasler Wolfgang E., Ebert Oliver, Thasler, Wolfgang E., Schmid Roland M., Marozin, Sabrina, De Toni, Enrico N., Kato, Nobuyuki, Marozin Sabrina, Wolfgang E Thasler, Wolfgang E. Thasler, Enrico N De Toni, Altomonte, Jennifer, Alexandra Junger, De Toni Enrico N., Altomonte Jennifer, Ebert, Oliver, Günter Schneider, Oliver Ebert, Sabrina Marozin, Junger Alexandra, Kato Nobuyuki, Roland M. Schmid, Junger, Alexandra, Schneider Günter, Nobuyuki Kato, Rizzani, Antonia, Antonia Rizzani   +32 more
core   +2 more sources

A VSV-based assay quantifies coronavirus Mpro/3CLpro/Nsp5 main protease activity and chemical inhibition

Communications Biology, 2022
A vesicular stomatitis virus (VSV)-based assay enables high-throughput screening for small molecular protease inhibitors that can block viral proteases, like the Mpro/3CLpro/Nsp5 in SARS-CoV-2.
Emmanuel Heilmann, Francesco Costacurta, Stephan Geley, Seyad Arad Mogadashi, Andre Volland, Bernhard Rupp, Reuben Stewart Harris, Dorothee von Laer   +7 more
doaj   +1 more source

Use of Recombinant Virus Replicon Particles for Vaccination against Mycobacterium ulcerans Disease. [PDF]

, 2015
Buruli ulcer, caused by infection with Mycobacterium ulcerans, is a necrotizing disease of the skin and subcutaneous tissue, which is most prevalent in rural regions of West African countries.
Kerber, Sarah, Zimmer, Gert, Miriam Bolz, Sarah Kerber (421868), Bolz, Miriam, Gerd Pluschke, Miriam Bolz (309717), Gert Zimmer, Sarah Kerber, Gerd Pluschke (7855), Pluschke, Gerd, Gert Zimmer (223023)   +11 more
core   +3 more sources