Proteins of Vesicular Stomatitis Virus and of Phenotypically Mixed Vesicular Stomatitis Virus-Simian Virus 5 Virions [PDF]
Journal of Virology, 1971 The identity of the glycoprotein of vesicular stomatitis virus (VSV) as the spike protein has been confirmed by the removal of the spikes with a protease from Streptomyces griseus , leaving bullet-shaped particles bounded by a smooth membrane.
J J, McSharry +2 more
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Evaluating Temperature Sensitivity of Vesicular Stomatitis Virus–Based Vaccines
Emerging Infectious Diseases, 2019 Use of the vesicular stomatitis virus (VSV)–based Ebola virus vaccine during outbreaks and the potential use of a similar VSV-based Lassa virus vaccine has raised questions about the vaccines’ stability should the cold chain fail.
Derek R. Stein +5 more
doaj +1 more source
Cytokine-modified VSV is attenuated for neural pathology, but is both highly immunogenic and oncolytic [PDF]
, 2009 Vesicular stomatitis virus (VSV), an enveloped, nonsegmented, negative-stranded RNA virus, is being tested by several laboratories as an antitumor agent.
Bidula, Sarah M +3 more
core +1 more source
Nature Communications, 2023 Clinical identification and fundamental study of viruses rely on the detection of viral proteins or viral nucleic acids. Yet, amplification-based and antigen-based methods are not able to provide precise compositional information of individual virions ...
Qing Xia +8 more
doaj +1 more source
Preparation of Class Y Immunoglobulins that Neutralize the Marburg Virus
Проблемы особо опасных инфекций, 2021 The aim was to study the possibility of inducing Marburg-neutralizing chicken antibodies (MARV) using various immunogens.Materials and methods. Recombinant vaccinia virus expressing the surface glycoprotein (GP) transgene MARV of Musoke strain and ...
O. A. Polezhaeva +7 more
doaj +1 more source
Measuring Genetic Robustness in Vesicular Stomatitis Virus
Bio-Protocol, 2014 Genetic robustness is the ability of a genome to incorporate mutations with the result of no fitness changes. Thus, more robust viruses have an increased neutral mutation rate.
Isabel Novella
doaj +1 more source
The nucleocapsid of vesicular stomatitis virus [PDF]
Science China Life Sciences, 2012 The nucleocapsid of vesicular stomatitis virus serves as the genomic template for transcription and replication. The viral genomic RNA is sequestered in the nucleocapsid in every step of the virus replication cycle. The structure of the nucleocapsid and the entire virion revealed how the viral genomic RNA is encapsidated and packaged in the virus.
openaire +2 more sources
Safety of Recombinant VSV–Ebola Virus Vaccine Vector in Pigs
Emerging Infectious Diseases, 2015 The ongoing Ebola outbreak in West Africa has resulted in fast-track development of vaccine candidates. We tested a vesicular stomatitis virus vector expressing Ebola virus glycoprotein for safety in pigs.
Emmie de Wit +7 more
doaj +1 more source
Autographa californica Multicapsid Nucleopolyhedrovirus efficiently infects Sf9 cells and transduces mammalian cells via direct fusion with the plasma membrane at low pH [PDF]
, 2010 The budded virus (BV) of the Autographa californica multicapsid nucleopolyhedrovirus (AcMNPV) infects insect cells and transduces mammalian cells mainly through the endocytosis pathway.
Dong, S. +6 more
core +2 more sources
Activation of Nrf2 signaling augments Vesicular Stomatitis Virus Oncolysis via Autophagy-Driven Suppression of Antiviral Immunity [PDF]
, 2017 Oncolytic viruses (OVs) offer a promising therapeutic approach to treat multiple types of cancer. In this study, we show that the manipulation of the anti-oxidant network via transcription factor Nrf2 augments vesicular stomatitis virus Δ51 (VSVΔ51 ...
David Olagnier +85 more
core +4 more sources