Results 41 to 50 of about 1,140,792 (221)
Immunogenicity of propagation-restricted vesicular stomatitis virus encoding Ebola virus glycoprotein in guinea pigs. [PDF]
, 2018 Vesicular stomatitis virus (VSV) expressing the Ebola virus (EBOV) glycoprotein (GP) in place of the VSV glycoprotein G (VSV/EBOV-GP) is a promising EBOV vaccine candidate which has already entered clinical phase 3 studies.
Zimmer, Gert +7 more
core +2 more sources
Nature Communications, 2023 Clinical identification and fundamental study of viruses rely on the detection of viral proteins or viral nucleic acids. Yet, amplification-based and antigen-based methods are not able to provide precise compositional information of individual virions ...
Qing Xia +8 more
doaj +1 more source
Interactions between vaccinia virus and sensitized macrophages in vitro [PDF]
, 1975 The action of peritoneal exudate cells (PEC) from normal and vaccinia virus infected mice on infectious vaccinia virus particles was investigatedin vitro. PEC from immune mice showed a significantly higher infectivity titre reduction (virus clearance, VC)
Kruse, F. +5 more
core +1 more source
Measuring Genetic Robustness in Vesicular Stomatitis Virus
Bio-Protocol, 2014 Genetic robustness is the ability of a genome to incorporate mutations with the result of no fitness changes. Thus, more robust viruses have an increased neutral mutation rate.
Isabel Novella
doaj +1 more source
Oncolytic vesicular stomatitis virus expressing interferon-γ has enhanced therapeutic activity
Molecular Therapy: Oncolytics, 2016 Oncolytic viruses are known to stimulate the antitumor immune response by specifically replicating in tumor cells. This is believed to be an important aspect of the durable responses observed in some patients and the field is rapidly moving toward ...
M. Bourgeois-Daigneault +13 more
semanticscholar +1 more source
Vesicular stomatitis virus N and NS proteins form multiple complexes. [PDF]
, 1986 The vesicular stomatitis virus nucleocapsid protein, N, associated specifically with the viral phosphoprotein, NS, in an in vitro system which supported vesicular stomatitis virus RNA replication. Essentially all the N protein was found complexed with NS.
Arnheiter, Heinz +2 more
core +1 more source
Protocol for constructing and characterizing recombinant vectored vaccines for rabies virus
STAR ProtocolsSummary: Recombinant vectored vaccines provide economical, rapidly engineered, and tailored immunization strategies. Here, we present a protocol for constructing and characterizing recombinant vectored vaccines for rabies virus (RV).
Manar E. Khalifa, Muhammad Munir
doaj +1 more source
Safety of Recombinant VSV–Ebola Virus Vaccine Vector in Pigs
Emerging Infectious Diseases, 2015 The ongoing Ebola outbreak in West Africa has resulted in fast-track development of vaccine candidates. We tested a vesicular stomatitis virus vector expressing Ebola virus glycoprotein for safety in pigs.
Emmie de Wit +7 more
doaj +1 more source
A Recombinant Vesicular Stomatitis Virus Ebola Vaccine
New England Journal of Medicine, 2015 Background The worst Ebola virus disease (EVD) outbreak in history has resulted in more than 28,000 cases and 11,000 deaths. We present the final results of two phase 1 trials of an attenuated, replication‐competent, recombinant vesicular stomatitis ...
J. Regules +39 more
semanticscholar +1 more source
Role of lipids on entry and exit of bluetongue virus, a complex non-enveloped virus. [PDF]
, 2010 Non-enveloped viruses such as members of Picornaviridae and Reoviridae are assembled in the cytoplasm and are generally released by cell lysis. However, recent evidence suggests that some non-enveloped viruses exit from infected cells without lysis ...
Roy, Polly +5 more
core +1 more source