Results 61 to 70 of about 61,850 (209)

Producing Vesicular Stomatitis Virus G (VSVG) Protein and Assessment of its Cytotoxic Activity against Breast Cancer Cells

open access: yesمجله دانشکده پزشکی اصفهان, 2015
Background: The vesicular stomatitis virus G (VSVG) protein is a transmembran glycoprotein, which is involved in virus attachment to the specific receptor at the cell surface. This protein has been widely used to study therapeutic gene delivery. However,
Fereshteh Ghandehari   +3 more
doaj  

Oncolytic virotherapy induced CSDE1 neo-antigenesis restricts VSV replication but can be targeted by immunotherapy

open access: yesNature Communications, 2021
Oncolytic viruses, such as vesicular stomatitis virus (VSV), are a promising class of cancer therapeutics. Here the authors report that a mutation in the CSDE1 gene renders cancer cells resistant to VSV replication and oncolysis, but a mutation-derived ...
Timothy Kottke   +21 more
doaj   +1 more source

Post-translational processing of the glycoproteins of lymphocytic choriomeningitis virus. [PDF]

open access: yes, 1990
Intracellular events in the synthesis, glycosylation, and transport of the lymphocytic choriomeningitis virus (LCMV) glycoproteins have been examined. We have shown by N-glycanase digestion that LCMV strain Arm-4 bears five oligosaccharides on GP-1 and ...
Buchmeier, MJ   +3 more
core  

Conformational spread as a mechanism for cooperativity in the bacterial flagellar switch [PDF]

open access: yes, 2010
The bacterial flagellar switch that controls the direction of flagellar rotation during chemotaxis has a highly cooperative response. This has previously been understood in terms of the classic two-state, concerted model of allosteric regulation.
F. Bai   +29 more
core   +3 more sources

Polyadenylation of Vesicular Stomatitis Virus mRNA [PDF]

open access: yesJournal of Virology, 1974
Vesicular stomatitis virus (VSV) mRNA isolated from infected cell polysomes contains polyadenylic acid [poly(A)] sequences. Detergent-activated purified virions in vitro can transcribe complementary RNA, which has sedimentation properties similar to mRNA, and this RNA also contains poly(A) sequences.
openaire   +2 more sources

Engineering a serum-resistant and thermostable vesicular stomatitis virus G glycoprotein for pseudotyping retroviral and lentiviral vectors. [PDF]

open access: yes, 2013
Vesicular stomatitis virus G glycoprotein (VSV-G) is the most widely used envelope protein for retroviral and lentiviral vector pseudotyping; however, serum inactivation of VSV-G pseudotyped vectors is a significant challenge for in vivo gene delivery ...
Hwang, B-Y, Schaffer, DV
core  

Vesicular Stomatitis Virus (VSV) Therapy of Tumors [PDF]

open access: yesIUBMB Life, 2000
AbstractVesicular stomatitis virus (VSV) is an essentially nonpathogenic negative‐stranded RNA virus, the replication of which is extremely sensitive to the antiviral effects of interferon (IFN). We demonstrate here that VSV selectively induces the cytolysis of numerous transformed human cell lines in vitro, with all the morphological characteristics ...
S, Balachandran, G N, Barber
openaire   +2 more sources

Human Tibroviruses: Commensals or Lethal Pathogens?

open access: yesViruses, 2020
Rhabdoviruses are a large and ecologically diverse family of negative-sense RNA viruses (Mononegavirales: Rhabdoviridae). These viruses are capable of infecting an unexpectedly wide variety of plants, vertebrates, and invertebrates distributed over all ...
Jens H. Kuhn   +3 more
doaj   +1 more source

Differentiation of Foot-and-Mouth Disease-Infected pigs from Vaccinated Pigs Using Antibody-Detecting Sandwich ELISA [PDF]

open access: yes, 2011
The presence of serum antibodies for nonstructural proteins of the foot-and-mouth disease virus (FMDV) can differentiate FMDV-infected animals from vaccinated animals.
Aldo DEKKER   +10 more
core   +3 more sources

Clonal variation in cell surface display of an H-2 protein lacking a cytoplasmic tail [PDF]

open access: yes, 1986
Truncated variants of the gene encoding H-2Ld, an integral membrane protein encoded by the major histocompatibility complex, were constructed by in vitro mutagenesis to elucidate the function of charged amino acids found on the cytoplasmic side of the ...
Hood, Leroy E., Zuñiga, Martha C.
core  

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