Results 81 to 90 of about 1,173 (138)
Multifaceted Roles of Chloroquines in Gastrointestinal Disorders and Beyond
Chloroquine (CQ) and hydroxychloroquine (HCQ) modulate lysosomal activity and autophagy, suppressing gastrointestinal inflammation and reshaping pathogenic microbiota. These mechanisms alleviate inflammatory bowel disease, inhibit associated tumor growth, and provide benefits in certain autoimmune and viral conditions.
Sihyun Jeong +3 more
wiley +1 more source
MORPHOLOGY OF VESICULAR STOMATITIS VIRUS [PDF]
T L, CHOW, F H, CHOW, R P, HANSON
openaire +2 more sources
Cultivation of Vesicular Stomatitis Virus
Carrel, Olitsky, and Long1 reported the successful cultivation of the virus of vesicular stomatitis of horses in 1928. In their cultivation experiments, guinea pig tissues were used throughout. The method they employed consisted in placing embryonic tissue or adult bone marrow in contact with the virus which had been suspended in Tyrode's solution for ...
Cox, H. R. +2 more
openaire +1 more source
This study employs an in silico virtual screening workflow to evaluate lactic acid bacteria (LAB)‐derived bacteriocins as potential inhibitors of the monkeypox virus DNA polymerase (MPDP). Protein‐peptide docking simulations using the HADDOCK platform revealed that Sakacin P and Mundticin KS possess the highest binding affinities for the MPDP target ...
Melisa Z. Karaman +6 more
wiley +1 more source
Inactivation of Vesicular Stomatitis Virus by Disinfectants
Twenty-four chemical disinfectants considered to be viricidal were tested. Ten disinfectants were not viricidal for vesicular stomatitis virus within 10 min at 20 C when an LD 50 titer of 10 8.5 virus units per 0.1 ml were to be inactivated.
openaire +2 more sources
ABSTRACT This study examined changes in anti‐Spike (anti‐S) antibodies (Abs) and type I interferon (IFN‐I) following the BNT162b2 vaccine in people living with HIV (PLWH) and analyzed the impact of demographic and immunological factors. In total, 75 PLWH and 28 healthy donors were followed at baseline (T0), at the second dose (T1), after the second ...
Federica Frasca +18 more
wiley +1 more source
The filovirus, Ebola virus (EBOV), causes outbreaks of EBOV disease (EVD) throughout equatorial Africa. ERVEBO is a replication-competent recombinant vesicular stomatitis virus-vectored vaccine encoding the EBOV glycoprotein (recombinant vesicular ...
Jonah Elliff +12 more
doaj +1 more source
Interferon Response and Viral Evasion by Members of the Family Rhabdoviridae
Like many animal viruses, those of the Rhabdoviridae family, are able to antagonize the type I interferon response and cause disease in mammalian hosts. Though these negative-stranded RNA viruses are very simple and code for as few as five proteins, they
Matthias J. Schnell +2 more
doaj +1 more source
Abstract Antigen‐processing and ‐presenting cells play a pivotal role in initiation of the antiviral immune response. The cellular adaption of dendritic cells to reduced oxygen and nutrition levels at the site of infection is regulated predominantly by the transcription factor complex hypoxia‐inducible factor‐1 (HIF‐1).
Timm Schreiber +8 more
wiley +1 more source
Cellular microRNAs Repress Vesicular Stomatitis Virus but Not Theiler’s Virus Replication
Picornavirus’ genomic RNA is a positive-stranded RNA sequence that also serves as a template for translation and replication. Cellular microRNAs were reported to interfere to different extents with the replication of specific picornaviruses, mostly ...
Aurélie De Cock, Thomas Michiels
doaj +1 more source

