Results 71 to 80 of about 61,850 (209)
mBio, 2019 Research progress over the past 20 years has yielded several experimental Ebola virus (EBOV) vaccine candidates, which were shown to be effective in nonhuman primates when given 28 days before a lethal challenge. Of these, the vesicular stomatitis virus (
Gary Wong
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Lysosomal Delivery of Bioactive Proteins to Living Human Cells via Engineered Exosomes [PDF]
, 2018 Exosomes are naturally secreted nanovesicles derived from mammalian cells that are used for intercellular communication in vivo. As a result, they can potentially be used for intracellular delivery of therapeutics for disease treatment. We have developed
Levy, Daniel
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BMC Microbiology, 2023 Background The emergence of different viral infections calls for the development of new, effective, and safe antiviral drugs. Glycyrrhiza glabra is a well-known herbal remedy possessing antiviral properties. Objective The objective of our research was to
Dalia Elebeedy +8 more
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The host-range tdCE phenotype of Chandipura virus is determined by mutations in the polymerase gene [PDF]
The emerging arbovirus Chandipura virus (CV) has been implicated in epidemics of acute encephalitis in India with high mortality rates. The isolation of temperature-dependent host-range (tdCE) mutants, which are impaired in growth at 39 °C in chick ...
Easton, A. J. (Andrew J.) +2 more
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Development of the nanobody display technology to target lentiviral vectors to antigen-presenting cells [PDF]
, 2012 Lentiviral vectors (LVs) provide unique opportunities for the development of immunotherapeutic strategies, as they transduce a variety of cells in situ, including antigen-presenting cells (APCs). Engineering LVs to specifically transduce APCs is required
Breckpot, Karine +10 more
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Pseudotypes of Vesicular Stomatitis Virus and Pichinde Virus
Journal of General Virology, 1979 Super-infection of Pichinde virus-infected cells with vesicular stomatitis virus (VSV) resulted in the production of pseudotype virus which was not neutralized by antiserum to VSV but which was neutralized by antiserum to Pichinde virus. Analysis of pseudotype virus production in relation to the kinetics of replication of Pichinde virus demonstrated ...
S, Sengupta, W E, Rawls
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The impact of hypoxia on oncolytic virotherapy [PDF]
, 2011 The hypoxic tumor microenvironment plays significant roles in tumor cell metabolism and survival, tumor growth, and progression. Hypoxia modulates target genes in target cells mainly through an oxygen-sensing signaling pathway mediated by hypoxia ...
Sheng Guo, Z
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Cultivation of Vesicular Stomatitis Virus
Experimental Biology and Medicine, 1933 Carrel, Olitsky, and Long1 reported the successful cultivation of the virus of vesicular stomatitis of horses in 1928. In their cultivation experiments, guinea pig tissues were used throughout. The method they employed consisted in placing embryonic tissue or adult bone marrow in contact with the virus which had been suspended in Tyrode's solution for ...
Cox, H. R. +2 more
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Semina: Ciências Agrárias, 2019 This study aimed to determine the prevalence of vesicular stomatitis virus (VSV) in buffaloes in the state of Paraíba, Northeastern Brazil. The study was carried out in 14 herds in the municipalities of Alagoa Nova, Areia, Campina Grande, Guarabira ...
Camila de Sousa Bezerra +9 more
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Molecular Therapy: Oncolytics, 2019 Vesicular stomatitis virus (VSV) represents an attractive oncolytic virotherapy platform because of its potent tumor cell-killing and immune-stimulating properties; yet the clinical translation of VSV faces numerous challenges, such as inefficient ...
Michael Karl Melzer +7 more
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