Results 31 to 40 of about 40,172 (184)

Measuring Genetic Robustness in Vesicular Stomatitis Virus

Bio-Protocol, 2014
Genetic robustness is the ability of a genome to incorporate mutations with the result of no fitness changes. Thus, more robust viruses have an increased neutral mutation rate.
Isabel Novella
doaj   +1 more source

Proteins of Vesicular Stomatitis Virus and of Phenotypically Mixed Vesicular Stomatitis Virus-Simian Virus 5 Virions [PDF]

Journal of Virology, 1971
The identity of the glycoprotein of vesicular stomatitis virus (VSV) as the spike protein has been confirmed by the removal of the spikes with a protease from Streptomyces griseus , leaving bullet-shaped particles bounded by a smooth membrane.
J J, McSharry, R W, Compans, P W, Choppin   +2 more
openaire   +2 more sources

Protocol for constructing and characterizing recombinant vectored vaccines for rabies virus

STAR Protocols
Summary: Recombinant vectored vaccines provide economical, rapidly engineered, and tailored immunization strategies. Here, we present a protocol for constructing and characterizing recombinant vectored vaccines for rabies virus (RV).
Manar E. Khalifa, Muhammad Munir
doaj   +1 more source

Safety of Recombinant VSV–Ebola Virus Vaccine Vector in Pigs

Emerging Infectious Diseases, 2015
The ongoing Ebola outbreak in West Africa has resulted in fast-track development of vaccine candidates. We tested a vesicular stomatitis virus vector expressing Ebola virus glycoprotein for safety in pigs.
Emmie de Wit, Andrea Marzi, Trenton Bushmaker, Doug Brining, Dana Scott, Juergen A. Richt, Thomas W. Geisbert, Heinz Feldmann   +7 more
doaj   +1 more source

Vesicular Stomatitis Virus–Based Vaccines against Lassa and Ebola Viruses

Emerging Infectious Diseases, 2015
We demonstrated that previous vaccination with a vesicular stomatitis virus (VSV)–based Lassa virus vaccine does not alter protective efficacy of subsequent vaccination with a VSV-based Ebola virus vaccine.
Andrea Marzi, Friederike Feldmann, Thomas W. Geisbert, Heinz Feldmann, David Safronetz   +4 more
doaj   +1 more source

Eradication of Swine Vesicular Disease in Italy

Viruses, 2020
Swine vesicular disease (SVD) is a contagious viral disease of pigs clinically indistinguishable from other vesicular diseases, such as foot and mouth disease, vesicular stomatitis, vesicular exanthema of swine, and idiopathic vesicular disease. In Italy,
Marco Tamba, Francesco Plasmati, Emiliana Brocchi, Luigi Ruocco   +3 more
doaj   +1 more source

Tamoxifen Protects from Vesicular Stomatitis Virus Infection

Pharmaceuticals, 2019
Background: Tamoxifen (TAM) is an estrogen-receptor antagonist, widely used in the adjuvant treatment of early stage estrogen-sensitive breast cancer.
Lamin B. Cham, Sarah-Kim Friedrich, Tom Adomati, Hilal Bhat, Maximilian Schiller, Michael Bergerhausen, Thamer Hamdan, Fanghui Li, Yara Maria Machlah, Murtaza Ali, Vikas Duhan, Karl Sebastian Lang, Justa Friebus-Kardash, Judith Bezgovsek   +13 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Oncolytic viruses-modulated immunogenic cell death, apoptosis and autophagy linking to virotherapy and cancer immune response

Frontiers in Cellular and Infection Microbiology, 2023
Recent reports have revealed that oncolytic viruses (OVs) play a significant role in cancer therapy. The infection of OVs such as oncolytic vaccinia virus (OVV), vesicular stomatitis virus (VSV), parvovirus, mammalian reovirus (MRV), human adenovirus ...
Yi-Ying Wu, Yi-Ying Wu, Te-Kai Sun, Ming-Shan Chen, Muhammad Munir, Hung-Jen Liu, Hung-Jen Liu, Hung-Jen Liu, Hung-Jen Liu, Hung-Jen Liu   +9 more
doaj   +1 more source

Polyadenylation of Vesicular Stomatitis Virus mRNA [PDF]

Journal of Virology, 1974
Vesicular stomatitis virus (VSV) mRNA isolated from infected cell polysomes contains polyadenylic acid [poly(A)] sequences. Detergent-activated purified virions in vitro can transcribe complementary RNA, which has sedimentation properties similar to mRNA, and this RNA also contains poly(A) sequences.
openaire   +2 more sources