Results 31 to 40 of about 1,173 (138)
The synthetic futures of vesicular stomatitis virus [PDF]
Recent advances in synthetic biology have opened up the possibility of finely engineering viral genomes with the goal to understand and prevent viral diseases [1]. Vesicular stomatitis virus (VSV) is one of the most promising viruses for engineering vaccines and oncolytic therapies [2].
Overend, Christopher +2 more
openaire +2 more sources
Measuring Genetic Robustness in Vesicular Stomatitis Virus
Genetic robustness is the ability of a genome to incorporate mutations with the result of no fitness changes. Thus, more robust viruses have an increased neutral mutation rate.
Isabel Novella
doaj +1 more source
Surface Structure of Vesicular Stomatitis Virus
Summary Trypsin (0.1 mg./ml.) reduced the infectivity of vesicular stomatitis virus by 5 log. within 5 min. and destroyed immunizing activity. It also destroyed the complement-fixing activity against antiserum to the virus but the activity against antiserum to host cells was unaffected.
B, Cartwright, C J, Smale, F, Brown
openaire +2 more sources
Protocol for constructing and characterizing recombinant vectored vaccines for rabies virus
Summary: Recombinant vectored vaccines provide economical, rapidly engineered, and tailored immunization strategies. Here, we present a protocol for constructing and characterizing recombinant vectored vaccines for rabies virus (RV).
Manar E. Khalifa, Muhammad Munir
doaj +1 more source
Safety of Recombinant VSV–Ebola Virus Vaccine Vector in Pigs
The ongoing Ebola outbreak in West Africa has resulted in fast-track development of vaccine candidates. We tested a vesicular stomatitis virus vector expressing Ebola virus glycoprotein for safety in pigs.
Emmie de Wit +7 more
doaj +1 more source
Proteins of Vesicular Stomatitis Virus and of Phenotypically Mixed Vesicular Stomatitis Virus-Simian Virus 5 Virions [PDF]
The identity of the glycoprotein of vesicular stomatitis virus (VSV) as the spike protein has been confirmed by the removal of the spikes with a protease from Streptomyces griseus , leaving bullet-shaped particles bounded by a smooth membrane.
J J, McSharry +2 more
openaire +2 more sources
Vesicular Stomatitis Virus Transmission Dynamics Within Its Endemic Range in Chiapas, Mexico
Vesicular stomatitis virus (VSV), comprising vesicular stomatitis New Jersey virus (VSNJV) and vesicular stomatitis Indiana virus (VSIV), emerges from its focus of endemic transmission in Southern Mexico to cause sporadic livestock epizootics in the ...
Lawrence H. Zhou +12 more
doaj +1 more source
Vesicular Stomatitis Virus–Based Vaccines against Lassa and Ebola Viruses
We demonstrated that previous vaccination with a vesicular stomatitis virus (VSV)–based Lassa virus vaccine does not alter protective efficacy of subsequent vaccination with a VSV-based Ebola virus vaccine.
Andrea Marzi +4 more
doaj +1 more source
Eradication of Swine Vesicular Disease in Italy
Swine vesicular disease (SVD) is a contagious viral disease of pigs clinically indistinguishable from other vesicular diseases, such as foot and mouth disease, vesicular stomatitis, vesicular exanthema of swine, and idiopathic vesicular disease. In Italy,
Marco Tamba +3 more
doaj +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source

