Results 21 to 30 of about 61,850 (209)

A VSV-based assay quantifies coronavirus Mpro/3CLpro/Nsp5 main protease activity and chemical inhibition

open access: yesCommunications Biology, 2022
A vesicular stomatitis virus (VSV)-based assay enables high-throughput screening for small molecular protease inhibitors that can block viral proteases, like the Mpro/3CLpro/Nsp5 in SARS-CoV-2.
Emmanuel Heilmann   +7 more
doaj   +1 more source

Examination of vesicular stomatitis virus-induced morphology changes in individual Vero cells by QMod microscopy

open access: yesBioTechniques, 2020
Viral infection of cultured cells induces changes in the biophysical characteristics of the affected cells. Advanced microscopic cameras such as Ovizio’s QMod, coupled with the appropriate software, can measure a variety of characteristics on a per-cell ...
Isabel Scholz   +2 more
doaj   +1 more source

Carbohydrate Composition of Vesicular Stomatitis Virus [PDF]

open access: yesJournal of Virology, 1971
Analysis by gas-liquid chromatography of the trimethylsilylated sugar residues of purified vesicular stomatitis virus grown in L cells or chick embryo cells revealed the presence in the whole virion of four hexoses (glucose, galactose, mannose, and fucose), two hexosamines (glucosamine and galactosamine), and 34 to 40% neuraminic acid.
J J, McSharry, R R, Wagner
openaire   +2 more sources

Aptamer-facilitated Protection of Oncolytic Virus from Neutralizing Antibodies

open access: yesMolecular Therapy: Nucleic Acids, 2014
Oncolytic viruses promise to significantly improve current cancer treatments through their tumor-selective replication and multimodal attack against cancer cells.
Darija Muharemagic   +6 more
doaj   +1 more source

Autophagy gene activity may act as a key factor for sensitivity of tumor cells to oncolytic vesicular stomatitis virus [PDF]

open access: yes, 2016
Background: Beclin1 is an important, primary molecule for autophagy. Objectives: It is suggested that the control of the autophagy path increases the sensitivity of tumor cells to VSV.
Arefian, E.   +3 more
core   +2 more sources

Use of recombinant virus replicon particles for vaccination against Mycobacterium ulcerans disease [PDF]

open access: yes, 2015
Buruli ulcer, caused by infection with Mycobacterium ulcerans, is a necrotizing disease of the skin and subcutaneous tissue, which is most prevalent in rural regions of West African countries.
Bolz, Miriam   +3 more
core   +3 more sources

Restriction of HIV-1 replication in monocytes is abolished by Vpx of SIVsmmPBj [PDF]

open access: yes, 2009
Background: Human primary monocytes are refractory to infection with the human immunodeficiency virus 1 (HIV-1) or transduction with HIV-1-derived vectors.
Silke Schüle   +61 more
core   +10 more sources

Viroses confundíveis com febre aftosa Viral diseases to be differentiated from foot-and-mouth disease

open access: yesCiência Rural, 1996
Revisam-se as doenças que devem ser consideradas no diagnóstico diferencial de febre aftosa. Dentre as doenças vesiculares ou erosivas, descrevem-se os principais aspectos relacionados ao diagnóstico da estomatite vesicular, diarréia viral bovina, febre ...
Franklin Riet-Correa   +3 more
doaj   +1 more source

A method for the generation of pseudovirus particles bearing SARS coronavirus spike protein in high yields

open access: yesCell Structure and Function, 2022
The ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has threatened human health and the global economy. Development of additional vaccines and therapeutics is urgently required, but such development with live virus must be ...
Yoichiro Fujioka   +7 more
doaj   +1 more source

Fitness Determinations in Vesicular Stomatitis Virus

open access: yesBio-Protocol, 2014
Fitness is defined as the overall replicative ability. Testing whether a mutation (or combination of mutations) has an effect on fitness often relays on determining virus production as a surrogate measurement. However, viruses do not usually replicate in
Isabel Novella
doaj   +1 more source

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