Results 21 to 30 of about 45,278 (218)

Producing Vesicular Stomatitis Virus G (VSVG) Protein and Assessment of its Cytotoxic Activity against Breast Cancer Cells

مجله دانشکده پزشکی اصفهان, 2015
Background: The vesicular stomatitis virus G (VSVG) protein is a transmembran glycoprotein, which is involved in virus attachment to the specific receptor at the cell surface. This protein has been widely used to study therapeutic gene delivery. However,
Fereshteh Ghandehari, Mandana Behbahani, Abbasali Pourazar, Zahra Nourmohammadi   +3 more
doaj   +1 more source

Integrin Alpha E (CD103) Limits Virus-Induced IFN-I Production in Conventional Dendritic Cells

Frontiers in Immunology, 2021
Early and strong production of IFN-I by dendritic cells is important to control vesicular stomatitis virus (VSV), however mechanisms which explain this cell-type specific innate immune activation remain to be defined.
Vikas Duhan, Vikas Duhan, Vishal Khairnar, Vishal Khairnar, Simo Kitanovski, Thamer A. Hamdan, Thamer A. Hamdan, Andrés D. Klein, Andrés D. Klein, Judith Lang, Murtaza Ali, Tom Adomati, Hilal Bhat, Hilal Bhat, Sarah-Kim Friedrich, Fanghui Li, Philippe Krebs, Anthony H. Futerman, Marylyn M. Addo, Marylyn M. Addo, Marylyn M. Addo, Cornelia Hardt, Daniel Hoffmann, Philipp A. Lang, Karl S. Lang   +24 more
doaj   +1 more source

CONSTRUCTION AND STUDY OF Althaea officinalis TRANSGENIC ROOTS CULTURE WITH HUMAN INTERFERON α2B GENE [PDF]

Biotechnologia Acta, 2013
The aim of our work was to obtain Althaea officinalis L. «hairy» root culture with human interferon α2b gene (ifn-α2b), to measure fructans content and antiviral activity of extracts from the transgenic roots. Transformation of leaf and root explants was
N. A. Matvieieva, Yu. I. Kudriavets, A. A. Lichova, O. Yu. Kvasko, A. M. Shachovsky   +4 more
doaj   +1 more source

Cell cycle progression or translation control is not essential for vesicular stomatitis virus oncolysis of hepatocellular carcinoma. [PDF]

, 2010
The intrinsic oncolytic specificity of vesicular stomatitis virus (VSV) is currently being exploited to develop alternative therapeutic strategies for hepatocellular carcinoma (HCC). Identifying key regulators in diverse transduction pathways that define
Enrico N. De Toni, Jennifer Altomonte, Roland M Schmid, Schneider, Günter, Schmid, Roland M., Rizzani Antonia, Thasler Wolfgang E., Ebert Oliver, Thasler, Wolfgang E., Schmid Roland M., Marozin, Sabrina, De Toni, Enrico N., Kato, Nobuyuki, Marozin Sabrina, Wolfgang E Thasler, Wolfgang E. Thasler, Enrico N De Toni, Altomonte, Jennifer, Alexandra Junger, De Toni Enrico N., Altomonte Jennifer, Ebert, Oliver, Günter Schneider, Oliver Ebert, Sabrina Marozin, Junger Alexandra, Kato Nobuyuki, Roland M. Schmid, Junger, Alexandra, Schneider Günter, Nobuyuki Kato, Rizzani, Antonia, Antonia Rizzani   +32 more
core   +1 more source

Use of Recombinant Virus Replicon Particles for Vaccination against Mycobacterium ulcerans Disease. [PDF]

, 2015
Buruli ulcer, caused by infection with Mycobacterium ulcerans, is a necrotizing disease of the skin and subcutaneous tissue, which is most prevalent in rural regions of West African countries.
Kerber, Sarah, Zimmer, Gert, Miriam Bolz, Sarah Kerber (421868), Bolz, Miriam, Gerd Pluschke, Miriam Bolz (309717), Gert Zimmer, Sarah Kerber, Gerd Pluschke (7855), Pluschke, Gerd, Gert Zimmer (223023)   +11 more
core   +1 more source

A VSV-based assay quantifies coronavirus Mpro/3CLpro/Nsp5 main protease activity and chemical inhibition

Communications Biology, 2022
A vesicular stomatitis virus (VSV)-based assay enables high-throughput screening for small molecular protease inhibitors that can block viral proteases, like the Mpro/3CLpro/Nsp5 in SARS-CoV-2.
Emmanuel Heilmann, Francesco Costacurta, Stephan Geley, Seyad Arad Mogadashi, Andre Volland, Bernhard Rupp, Reuben Stewart Harris, Dorothee von Laer   +7 more
doaj   +1 more source

Viroses confundíveis com febre aftosa Viral diseases to be differentiated from foot-and-mouth disease

Ciência Rural, 1996
Revisam-se as doenças que devem ser consideradas no diagnóstico diferencial de febre aftosa. Dentre as doenças vesiculares ou erosivas, descrevem-se os principais aspectos relacionados ao diagnóstico da estomatite vesicular, diarréia viral bovina, febre ...
Franklin Riet-Correa, Valéria Moojen, Paulo Michel Roehe, Rudi Weiblen   +3 more
doaj   +1 more source

Model for Vesicular Stomatitis Virus [PDF]

Journal of Virology, 1972
Vesicular stomatitis virus contains single-stranded ribonucleic acid of molecular weight 3.6 × 10 6 and three major proteins with molecular weights of 75 × 10 3 , 57 × 10 3 , and 32.5 × 10 3 .
B, Cartwright, C J, Smale, F, Brown, R, Hull   +3 more
openaire   +2 more sources

Aptamer-facilitated Protection of Oncolytic Virus from Neutralizing Antibodies

Molecular Therapy: Nucleic Acids, 2014
Oncolytic viruses promise to significantly improve current cancer treatments through their tumor-selective replication and multimodal attack against cancer cells.
Darija Muharemagic, Anna Zamay, Shahrokh M Ghobadloo, Laura Evgin, Anna Savitskaya, John C Bell, Maxim V Berezovski   +6 more
doaj   +1 more source

Atomic model of vesicular stomatitis virus and mechanism of assembly

Nature Communications, 2022
Zhou and Si et al. used cryogenic electron microscopy and tomography to delineate the molecular interactions among genomic RNA, nucleocapsid protein, matrix protein and glycoprotein in vesicular stomatitis virus and suggest a model of assembly.
Kang Zhou, Zhu Si, Peng Ge, Jun Tsao, Ming Luo, Z. Hong Zhou   +5 more
doaj   +1 more source