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Structural intermediates in the fusion‐associated transition of vesiculovirus glycoprotein [PDF]

open access: yesEMBO Journal, 2017
Vesiculoviruses enter cells by membrane fusion, driven by a large, low-pH-induced, conformational change in the fusion glycoprotein G that involves transition from a trimeric pre-fusion toward a trimeric post-fusion state via monomeric intermediates.
Yves Gaudin   +2 more
exaly   +5 more sources

Development of a reverse genetics system for snakehead vesiculovirus (SHVV)

open access: yesVirology, 2019
Snakehead vesiculovirus (SHVV) is a new rhabdovirus isolated from diseased hybrid snakehead fish (Channa maculate ♀ x Channa argus ♂) and has caused serious economic losses in snakehead fish culture in China. To better understand the pathogenicity of SHVV, we developed a reverse genetics system for SHVV by using human and fish cells.
Jiagang Tu, Jianguo Su, Jianguo Su
exaly   +3 more sources
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Pathogenicity of snakehead vesiculovirus in rice field eels (Monopterus albus)

Microbial Pathogenesis, 2017
Snakehead vesiculovirus (SHVV) has caused mass mortality to cultured snakehead fish in China, resulting in enormous economic losses in snakehead fish culture. In this report, the whole genome of SHVV was sequenced. Interestingly, it shared more than 94% nucleotide sequence identity with Monopterus albus rhabdovirus (MoARV), which has caused great ...
Jiagang Tu, Yunmao Huang, Wenjie Chen
exaly   +3 more sources

Hsp90 Is Required for Snakehead Vesiculovirus Replication via Stabilization of the Viral L Protein

open access: yesJournal of Virology, 2021
It has long been proposed that cellular proteins are involved in viral RNA synthesis via interacting with the viral polymerase protein. This study focused on identifying cellular proteins interacting with the SHVV L protein, studying the effects of their interactions on SHVV replication, and revealing the underlying mechanisms.
Jiagang Tu, Yong-An Zhang
exaly   +4 more sources

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