Results 61 to 70 of about 7,047 (158)

Identification of TPRA1 as a Novel Receptor and Predictive Biomarker for Oncolytic Virus M1

Advanced Science, Volume 12, Issue 48, December 29, 2025.
This study identifies transmembrane protein adipocyte‐associated 1 (TPRA1) as a novel receptor for oncolytic virus M1 (OVM). TPRA1's ectodomain binds OVM particles, while its intracellular domain facilitates virus internalization, promoting efficient viral entry.
Linyi Hu, Guigen Zhang, Yuan Lin, Shiming Yi, Jingyu Yang, Xueying Lin, Deli Song, Zhiheng Liu, Jiayu Zhang, Ying Zeng, Shanyu Huang, Zhen Fan, Jifu Zhang, Ying Liu, Cheng Hu, Wenbo Zhu, Wei Yin, Jun Hu, Guangmei Yan, Jing Cai, Jiankai Liang   +20 more
wiley   +1 more source

Investigação epidemiológica de Estomatite vesicular por achados clínicos em bovinos e equinos no Estado do Maranhão

Pesquisa Veterinária Brasileira, 2015
Resumo:A Estomatite Vesicular (EV) é uma doença infecciosa que acomete equinos, bovinos, suínos, mamíferos silvestres e humanos. Por apresentar sinais clínicos semelhantes a outras doenças vesiculares, principalmente, febre aftosa, sua presença em ...
Roberto C.N. de Arruda, José M.F. Segundo, Bruno A. Soares, Nelson R.S. Martins, Thales A. Barçante, Joziana M.P. Barçante   +5 more
doaj   +1 more source

Development of an inactivated candidate vaccine against Chandipura virus (Rhabdoviridae: Vesiculovirus)

Vaccine, 2011
A Vero cell based vaccine candidate against Chandipura (CHP) virus (Rhabdoviridae: Vesiculovirus), was developed and evaluated for immunogenicity in mice. Virus was purified by ultracentrifugation on 30% glycerol cushion followed by differential centrifugation on 10-60% sucrose gradient and inactivated with β-propio lactone at a concentration of 1:3500.
Jadi, R.S., Sudeep, A.B., Barde, P.V., Arankalle, V.A., Mishra, A.C.   +4 more
openaire   +2 more sources

Extensively harvested hay contaminated with common windgrass induced an ulcerative stomatitis–gingivitis outbreak in horses

Equine Veterinary Education, Volume 37, Issue 4, Page e67-e70, April 2025.
Summary After starting feeding on a new batch of hay, 29 out of 33 horses showed clinical signs of oral ulcerative and bleeding papules and mucous membrane erythema of the gingiva of the mandible within 2–3 days. The results of the complete blood cell count and biochemistry analysis did not yield significant findings in relation to horses affected by ...
I. Vervuert, S. Müller, H. Karl
wiley   +1 more source

Rhabdovirus matrix protein structures reveal a novel mode of self-association.

PLoS Pathogens, 2008
The matrix (M) proteins of rhabdoviruses are multifunctional proteins essential for virus maturation and budding that also regulate the expression of viral and host proteins. We have solved the structures of M from the vesicular stomatitis virus serotype
Stephen C Graham, René Assenberg, Olivier Delmas, Anil Verma, Alireza Gholami, Chiraz Talbi, Raymond J Owens, David I Stuart, Jonathan M Grimes, Hervé Bourhy   +9 more
doaj   +1 more source

Modified Alphavirus-Vesiculovirus Hybrid Vaccine Vectors for Homologous Prime-Boost Immunotherapy of Chronic Hepatitis B

Vaccines, 2020
Virus-like vesicles (VLV) are hybrid vectors based on an evolved Semliki Forest virus (SFV) RNA replicon and the envelope glycoprotein (G) from vesicular stomatitis virus (VSV).
Carolina Chiale, Timur O. Yarovinsky, Stephen W. Mason, Bhaskara R. Madina, Manisha Menon, Marie M. Krady, Safiehkhatoon Moshkani, Anasuya Chattopadhyay Pal, Bijan Almassian, John K. Rose, Michael D. Robek, Valerian Nakaar   +11 more
doaj   +1 more source

A Novel Protein NLRP12‐119aa that Prevents Rhabdovirus Replication by Disrupting the RNP Complex Formation

Advanced Science, Volume 12, Issue 12, March 27, 2025.
The NLRP12‐119aa protein exerts its antiviral effect by two distinct mechanisms. First, it competes with the N protein of rhabdoviruses for binding to the viral leRNA, thereby preventing the formation of the RNP complex. Second, NLRP12‐119aa directly interacts with the rhabdovirus N protein, destabilizing it and promoting its degradation, which ...
Weiwei Zheng, Xiangxiang Zhu, Tongtong Zhu, Qiang Luo, Yan Zhao, Tianjun Xu   +5 more
wiley   +1 more source

Parasitic and Viral Infection Rates in European Eels (Anguilla anguilla) in Four Spanish Mediterranean Wetlands

Journal of Applied Ichthyology, Volume 2025, Issue 1, 2025.
The European eel (Anguilla anguilla L. 1758) is a migratory fish species whose populations have undergone a severe collapse in numbers in recent decades. Infectious diseases are one of the factors contributing to the decline of European eels.
Elena Bereziuk, Alonso Pérez-Vegas, Elena Barcala, Diego Romero, Pilar Muñoz, Gournaga Biswas   +5 more
wiley   +1 more source

Comparação de dois testes de neutralização, utilizados no diagnóstico sorológico do vesiculovírus Piry

Revista de Saúde Pública, 1993
Realizou-se inquérito sorológico para pesquisar anticorpos neutralizantes contra o vesiculovírus Piry, na cidade de Catolândia-Bahia-Brasil. Duas técnicas de vírus-neutralização foram comparadas em cultura das células C6/36, com revelação pelo método ...
Tavares-Neto José, Owa Miyoco Abe, Rosa Amélia Travassos da, Vasconcelos Pedro, Figueiredo Luiz T.M.   +4 more
doaj  

Using Vesicular Stomatitis Virus as a Platform for Directed Protease Evolution

Current Protocols, Volume 4, Issue 12, December 2024.
Abstract Antiviral drugs are essential medications to save the lives of infected people. However, they are under constant threat to become ineffective as viruses evolve quickly. Studying the development of resistance is therefore paramount to understand the impact of mutations on pharmacological treatment and to make informed decisions.
Francesco Costacurta, Stefanie Rauch, Dorothee von Laer, Emmanuel Heilmann   +3 more
wiley   +1 more source