Results 41 to 50 of about 3,008,306 (295)

Lymphatic vessel density and function in experimental bladder cancer

BMC Cancer, 2007
The lymphatics form a second circulatory system that drains the extracellular fluid and proteins from the tumor microenvironment, and provides an exclusive environment in which immune cells interact and respond to foreign antigen. Both cancer and inflammation are known to induce lymphangiogenesis.
Maier Julie, Simpson Cindy, Davis Carole A, Neeman Michal, Abbott Andrew, Smith Nataliya, Towner Rheal, Saban Marcia R, Mémet Sylvie, Wu Xue-Ru, Saban Ricardo   +10 more
openaire   +3 more sources

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Water flow based vessel detection in retinal images

, 2006
Previous vessel segmentation methods mainly concentrate on the general structure, and often ignore the accuracy, smoothness and continuity of vessel boundaries. A water flow based method is proposed to solve the problem. It embodies the fluidity of water
M.S. Nixon, Nixon, Mark S, Liu, Xin U, X.U. Liu   +3 more
core   +2 more sources

The Effect of Myopia on Vessel Density in Glaucomatous Patients by Optical Coherence Tomography Angiography

, 2023
Saeed AM, Mohamed Anany, Mohamed A Awwad, Eman Sanad, Soha MM Eltohamy Department of Ophthalmology, Benha University Hospital, Benha, Qualubia, EgyptCorrespondence: Mohamed A Awwad, Department of Ophthalmology, Benha University Hospital, Benha, Qualubia,
AM S, Awwad MA, Anany M, Eltohamy SM, Sanad E   +4 more
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Comparison of Optical Coherence Tomography Angiography and Laser Speckle Flowgraphy for the Diagnosis of Normal-Tension Glaucoma

Journal of Ophthalmology, 2018
Purpose. To compare optical coherence tomography angiography (OCT-A) and laser speckle flowgraphy (LSFG) for the diagnosis of normal-tension glaucoma (NTG). Methods.
Asuka Takeyama, Kyoko Ishida, Ayako Anraku, Masahiro Ishida, Goji Tomita   +4 more
doaj   +1 more source

The chemokine receptors ACKR2 and CCR2 reciprocally regulate lymphatic vessel density [PDF]

, 2014
Macrophages regulate lymphatic vasculature development; however, the molecular mechanisms regulating their recruitment to developing, and adult, lymphatic vascular sites are not known.
Lee, Kit M, Graham, Delyth, Gerard J Graham, Delyth Graham, Robert JB Nibbs, Danuser, Renzo, Kit M Lee, Stein, Jens V., Nibbs, Robert J B, Nibbs, Robert J.B., Graham, Gerard J, Graham, Gerard J., Stein, Jens Volker, Lee, Kit M., Renzo Danuser, Jens V Stein   +15 more
core   +2 more sources

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Macular and optic disc vascular densities measured by optical coherence tomography angiography in pediatric patients with different amblyopia types

BMC Ophthalmology
Purpose The present study aimed to compare macular and peripapillary vascular density values measured by optical coherence tomography angiography (OCTA) in different types of amblyopia (ametropic amblyopia, anisometropic amblyopia, strabismic amblyopia ...
Merve Simsek, Yesim Oral, Muberra Akdogan, Mehmet Cem Sabaner, Cem Simsek   +4 more
doaj   +1 more source