Results 51 to 60 of about 3,157,082 (301)

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Microvascular Changes in Pituitary Adenoma Correlate with Structural Measurements and Visual Field Loss

Neuropsychiatric Disease and Treatment, 2023
Yaying Chen,1,2 Xiaojiao Li,2 Xiangyuan Song,2 Lin Cong,2 Yuyan Zhang1 1Department of Ophthalmology, Huadong Hospital, Fudan University School of Medicine, Shanghai, People’s Republic of China; 2Department of Ophthalmology, Huashan Hospital, Fudan ...
Chen Y, Li X, Song X, Cong L, Zhang Y
doaj  

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Optical Coherence Tomography Angiography Vessel Density in Healthy, Glaucoma Suspect, and Glaucoma Eyes

Journal of Current Ophthalmology
Purpose To evaluate and compare optical coherence tomography angiography (OCTA) retinal vasculature measurements in healthy, glaucoma suspect (GS), and glaucoma patients.
Umesh Belbase, Indra Man Maharjan, Anup Subedi   +2 more
doaj   +1 more source

Macular vessel density in central retinal artery occlusion with retinal arterial cannulation

Scientific Reports, 2023
To characterize and compare macular vessel density in central retinal artery occlusion (CRAO) eyes with retinal arterial cannulation and CRAO eyes with standard treatment. This study was Cross-sectional, observational study.
Naoki Soga, Shin Tanaka, Maiko Inoue, Tatsuya Inoue, Atsushi Hayashi, Eugene de Juan, Kazuaki Kadonosono   +6 more
doaj   +1 more source

Diagnostic abilities of vessel density and structural measurements.

, 2017
Sensitivity at 95% specificity of (a) optic nerve head vessel density and rim area, (b) peripapillary vessel density and retinal nerve fiber layer (RNFL) thickness and (c) superficial macular vessel density and ganglion cell complex (GCC) thickness ...
Narendra K. Puttaiah (3833503), Robert N. Weinreb (170002), Srilakshmi Dasari (3833488), Dhanaraj A. S. Rao (3833491), Carroll A. B. Webers (3833485), Mohammed Riyazuddin (3833506), Sathi Devi (3833497), Kaweh Mansouri (734957), Harsha L. Rao (639504), Zia S. Pradhan (3833500), Jayasree P. Venugopal (3833494)   +10 more
core   +1 more source

Linear regression analysis between clinical factors and average vessel density of inner and outer ring.

, 2021
Linear regression analysis between clinical factors and average vessel density of inner and outer ring.
Yong Il Shin (9411349), Gi Seok Park (11564864), Jung-Yeul Kim (6439670), Woo Hyuk Lee (9411361), Kee Sup Park (9611857), Hyung Bin Lim (2921772)   +5 more
core   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Vessel density values of superficial plexus, deep plexus and choriocapillaris.

, 2017
Vessel density values of superficial plexus, deep plexus and choriocapillaris.
Rodolfo Mastropasqua (840601), Marta Di Nicola (325339), Enrico Borrelli (750198), Luca Di Antonio (840603), Peter A. Mattei (139979), Lisa Toto (840602), Alfonso Senatore (3712747), Cesare Mariotti (3712750)   +7 more
core   +1 more source

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

FEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa, Mohammed Nooh, Akhil Geddati, Alex Dopico, Anna N. Bukiya   +4 more
wiley   +1 more source