Results 71 to 80 of about 588,440 (294)

In-vivo visualization of tumor microvessel density and response to anti-angiogenic treatment by high resolution MRI in mice. [PDF]

PLoS ONE, 2011
PURPOSE: Inhibition of angiogenesis has shown clinical success in patients with cancer. Thus, imaging approaches that allow for the identification of angiogenic tumors and the detection of response to anti-angiogenic treatment are of high clinical ...
Roland T Ullrich, Jan F Jikeli, Michael Diedenhofen, Philipp Böhm-Sturm, Maike Unruh, Stefan Vollmar, Mathias Hoehn   +6 more
doaj   +1 more source

Flow correlated percolation during vascular network formation in tumors

, 2005
A theoretical model based on the molecular interactions between a growing tumor and a dynamically evolving blood vessel network describes the transformation of the regular vasculature in normal tissues into a highly inhomogeneous tumor specific capillary
A.-L. Barabási, D. Stauffer, D.-S. Lee, H. Rieger, J. W. Baish, J. W. Baish, K. Bartha   +6 more
core   +1 more source

Coordination of Foliar and Wood Anatomical Traits Contributes to Tropical Tree Distributions and Productivity along the Malay-Thai Peninsula [PDF]

, 2009
Drought is a critical factor in plant species distributions. Much research points to its relevance even in moist tropical regions. Recent studies have begun to elucidate mechanisms underlying the distributions of tropical tree species with respect to ...
Baltzer, Jennifer L., Bunyavejchewin, Sarayudh, Davies, Stuart J., Grégoire, Dorothea M., Noor, N. Supardi M.   +4 more
core   +2 more sources

Assessment of podoplanin lymphatic vessel density in oral epithelial dysplasia

Journal of Oral and Maxillofacial Pathology, 2021
Background: Oral squamous cell carcinoma (OSCC) can be preceded by the appearance of lesions which have the potential to develop into cancer. Recently, it was suggested that the tumor-associated lymphatic vessels formation plays an active role in tumor progression and metastasis of several human malignancies including OSCC ...
Lunawat, Snehal Dilip, Prakash, Nilima, Pradeep, G. L., Chaware, Smita Jembu, Chaudhari, Nayana Rajendra, Salunkhe, Vaibhavi Parikshit   +5 more
openaire   +2 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Comparison of methods to quantify macular and peripapillary vessel density in optical coherence tomography angiography. [PDF]

PLoS ONE, 2018
PURPOSE:To compare macular and peripapillary vessel density values calculated on optical coherence tomography angiography (OCT-A) images with different algorithms, elaborate conversion formula, and compare the ability to discriminate healthy from ...
Alessandro Rabiolo, Francesco Gelormini, Riccardo Sacconi, Maria Vittoria Cicinelli, Giacinto Triolo, Paolo Bettin, Kouros Nouri-Mahdavi, Francesco Bandello, Giuseppe Querques   +8 more
doaj   +1 more source

Synthetic vascular ultrasound imaging through coupled fluid-structure interaction and ultrasound simulations [PDF]

, 2010
Although ultrasonic imaging is commonly applied in cardiovascular research and clinical practice, current blood flow and vessel wall imaging methods are still hampered by several limitations.
Degroote, Joris, Lovstakken, Lasse, Segers, Patrick, Swillens, Abigail, Vierendeels, Jan   +4 more
core   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Changes in Retinal Vasculature and Thickness after Small Incision Lenticule Extraction with Optical Coherence Tomography Angiography

Journal of Ophthalmology, 2019
Purpose. To evaluate the changes in retinal vessel density and thickness after small incision lenticule extraction (SMILE) with optical coherence tomography angiography (OCTA) in myopic patients. Methods.
Minjie Chen, Jinhui Dai, Lan Gong
doaj   +1 more source