Results 71 to 80 of about 157,979 (303)

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

3D Active Vessel Tracking Using an Elliptical Prior

IEEE Transactions on Image Processing, 2018
In this paper, we propose a novel vessel tracking method, called active vessel tracking (AVT). The proposed method retains the major advantages that most 2D segmentation methods have demonstrated for 3D tracking while overcoming the drawbacks of previous 3D vessel tracking methods. Under the assumption that the vessel is cylindrical, thereby making its
Jiwoo Kang, Suwoong Heo, Woo Jin Hyung, Joon Seok Lim, Sanghoon Lee   +4 more
openaire   +3 more sources

Spleen‐Targeting Biomimetic Hybrid Nanocarriers for Systemic Immune Reprogramming in Colitis: RBC Membrane Vesicle‐Fused Lipid Nanoparticles

Advanced Functional Materials, EarlyView.
A spleen‐targeting hybrid nanoplatform (RBCMV‐LNP‐RP) harnessing erythrophagocytosis mimics senescent red blood cell clearance to achieve spleen‐specific delivery of rapamycin. This biomimetic system enables selective accumulation in splenic macrophages, orchestrating systemic immune reprogramming and promoting mucosal healing in an inflammatory bowel ...
Jun Kwon, Hee Su Sohn, Jong Sang Yoon, So Won Jeon, Hee Gyeong Ko, Min‐Ho Kang, Jisun Lee, Jae‐Hwan Nam, Louis T. Merriam, Edy Y. Kim, Han Young Kim   +10 more
wiley   +1 more source

Trajectory Tracking Control of an Autonomous Vessel in the Presence of Unknown Dynamics and Disturbances

Mathematics
We present a proportional–integral–derivative-based controller plus an adaptive slide surface to solve the trajectory tracking control problem for a fully actuated vessel with unknown parameters perturbed by slowly varying external unknown dynamics.
Carlos Aguilar-Ibanez, Miguel S. Suarez-Castanon, Eloísa García-Canseco, Jose de Jesus Rubio, Ricardo Barron-Fernandez, Juan Carlos Martinez   +5 more
doaj   +1 more source

A novel method for blood vessel detection from retinal images

BioMedical Engineering OnLine, 2010
Background The morphological changes of the retinal blood vessels in retinal images are important indicators for diseases like diabetes, hypertension and glaucoma. Thus the accurate segmentation of blood vessel is of diagnostic value.
Luo Shuqian, Xu Lili
doaj   +1 more source

Observations of River Topography and Flow Around Bridges [PDF]

, 2009
This investigation was motivated by the amount of river, estuarine, and coastal infrastructure that is susceptible to extreme wave and flooding events. The high velocities and resulting shear stresses associated with high flow velocities are capable of ...
Lippmann, Thomas C.
core   +1 more source

Coronary Artery Centerline Extraction in Cardiac CT Angiography Using a CNN-Based Orientation Classifier

, 2018
Coronary artery centerline extraction in cardiac CT angiography (CCTA) images is a prerequisite for evaluation of stenoses and atherosclerotic plaque. We propose an algorithm that extracts coronary artery centerlines in CCTA using a convolutional neural ...
Išgum, Ivana, Leiner, Tim, van Hamersvelt, Robbert W., Viergever, Max A., Wolterink, Jelmer M.   +4 more
core   +1 more source

An All‐Optical Driven Bio‐Photovoltaic Interface for Active Control of Live Cells

Advanced Functional Materials, EarlyView.
Bio‐photovoltaic Interface (BIO‐PV‐I) for live cell manipulation is presented. BIO‐PV‐I can be activated non‐invasively and remotely to control the spatial motility, adhesion, and morphology of cells adhering to it. BIO‐PV‐I uses a patterned light‐induced electric potential in iron‐doped lithium niobate crystals whose light‐driven and reversible nature,
Lisa Miccio, Martina Mugnano, Valentina Marchesano, Alejandro Calabuig, Zhe Wang, Gennaro Giordano, Francesca Borrelli, Simonetta Grilli, Pietro Ferraro   +8 more
wiley   +1 more source

Nonlinear tracking control of underactuated surface vessel [PDF]

Proceedings of the 2005, American Control Conference, 2005., 2005
We consider in this paper the tracking control problem of an underactuated surface vessel. Based on the cascaded structure of tracking error dynamics, we present two new tracking controllers using Barbalat's lemma and back-stepping techniques under mild assumptions on the reference trajectory.
Dong, Wenjie, Guo, Yi
openaire   +1 more source

Locating a Mate in 3D: the Case of Temora Longicornis [PDF]

, 1998
Using laser optics to illuminate high–resolution video–recordings, we revealed behavioural mechanisms through which males of the calanoid copepod species Temora longicornis locate females. Males of T.
Colin, Sean, Doall, Michael H., Strickler, J. Rudi, Yen, Jeannette   +3 more
core   +1 more source