Results 91 to 100 of about 23,096 (266)
British Journal of Clinical Pharmacology, EarlyView.Regulators use expedited approval pathways to speed market approval and patient access to promising new drugs. However, there is uncertainty about whether these pathways are successful in approving drugs with significant therapeutic advantages. This systematic review aims to examine the safety, effectiveness and cost‐effectiveness of drugs approved via
Ashleigh Hooimeyer +4 more
wiley +1 more source
Tobramycin pharmacokinetic and pharmacodynamic targets in people with cystic fibrosis
British Journal of Clinical Pharmacology, EarlyView.Intravenous tobramycin is a first‐line treatment for Pseudomonas aeruginosa infection in people with cystic fibrosis (CF). Tobramycin exhibits concentration‐dependent activity; however, excess drug exposure can lead to nephrotoxicity and ototoxicity. While dosing typically targets serum peak (Cmax) and trough (Cmin) concentrations, the area under the ...
Kiera H. Harwood +6 more
wiley +1 more source
British Educational Research Journal, EarlyView.Abstract This study addresses the gap in rigorous evaluation of inclusive Citizenship Education methods in reducing gender and socioeconomic inequalities in political self‐efficacy. This article tests the effectiveness of two pedagogical approaches: counter‐narratives and think‐pair‐share.
Bryony Hoskins +2 more
wiley +1 more source
Humans are not unique: difficult birth is common in placental mammals
Biological Reviews, EarlyView.ABSTRACT Human childbirth is widely presumed to be uniquely difficult and dangerous compared to birth in other mammals. Tight fetopelvic proportions can result in obstructed labour and contribute to high rates of maternal and neonatal mortality. Ideas summarised under the ‘obstetrical dilemma’ have contributed to this assumption by explaining difficult
Nicole D. S. Grunstra
wiley +1 more source
Business Strategy and the Environment, EarlyView.ABSTRACT In response to growing global challenges, this study explores how social entrepreneurship within the Edible City movement contributes to building resilient, sustainable, and equitable urban food systems. Drawing on semistructured interviews with over 70 stakeholders across five cities—Berlin, Andernach, Oslo, Rotterdam, and Havana—we ...
Ina Säumel +6 more
wiley +1 more source
Journal of Indian Academy of Oral Medicine and Radiology, 2003 Lipoma is a benign, slowly growing encapsulated neoplasm, composed of matured fat cells that occurs with relatively rare frequency in oral cavity. According to the reported cases, the involved sites in order of frequency are buccal mucosa, tongue, floor ...
Parita Chitroda, Jigna Shah
doaj
Growth Strategy of Circular Startups
Business Strategy and the Environment, EarlyView.ABSTRACT Circular startups (CSUs) play a crucial role in the circular transition by developing circular business models (CBMs) that minimise resource use and narrow material and energy loops. However, empirical research on how CBMs shape growth strategies and how ecosystems enable or constrain scaling remains limited.
Gustavo Dalmarco +3 more
wiley +1 more source
Business Strategy and the Environment, EarlyView.ABSTRACT This study analyzed Industry 4.0 (I4.0) technology applications in agribusiness and the role of strategic stakeholders, engagement methods, and other critical aspects data sharing, confidentiality, integrity, decision‐making, and sector‐specific requirements in promoting circularity.
Simone Sehnem +3 more
wiley +1 more source
Carnets de Géologie, 2009 The species Krithe gnoma was described from Holocene sediments on the continental margin of Brazil, where it occurs on both shelf and slope. The shelf distribution of this species is restricted to those areas influenced by the Malvinas current between 32°
Do Carmo Dermeval Aparecido +3 more
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Translating Circularity Into Strategy: A Governance Meta‐Capability Framework
Business Strategy and the Environment, EarlyView.ABSTRACT Firms struggle to transition to circular economy (CE) models, often citing external barriers. Yet some firms succeed, whereas others fail: Why? We argue that success depends on a specific governance capability—a meta‐capability that allows firms to (1) sense and strategically reframe CE imperatives, (2) seize opportunities by aligning diverse ...
Felix Carl Schultz +1 more
wiley +1 more source