Results 91 to 100 of about 282,541 (285)

Bioorthogonal Fluorogenic Reporters for Noninvasive Imaging and Urinalysis of Immunotherapeutic Response in Renal Cell Carcinoma

Advanced Science, EarlyView.
This study reported renal‐clearable bio‐orthogonal near‐infrared fluorogenic probes (BGRs) that specifically imaging and urinalysis of granzyme B for dynamic evaluation of RCC immunotherapy. BGRs not only differentiate immunotherapeutic responses in orthotopic RCC mice, but also enable sensitive optical urinalysis of granzyme B in clinical specimens ...
Xingyue Yang, Baoshuai Liang, Liangmin Fu, Weiliang Deng, Yuyan Jiang, Weiping Xu, Jinwei Chen, Ya Zhou, Ke Wu, Jiaguo Huang   +9 more
wiley   +1 more source

Educational Impact of a 3D Canine Vascular Simulator for Learning Anatomy and Interventional Radiology Techniques in Veterinary Training

Veterinary Sciences
Background: Simulation-based teaching is increasingly important in veterinary training, especially for learning anatomy and interventional techniques where real-life exposure is limited.
Sandra Lopez-Minguez, Iris Urbano, Ignacio de Blas, Cantal del Rio-Martinez, Cristina Bonastre, Jose Andres Guirola, Jose Benito Rodriguez, Francisco Javier Miana-Mena, Carolina Serrano-Casorran   +8 more
doaj   +1 more source

Review of Rabies Preventions and Control [PDF]

, 2017
Rabies is an acute viral infection of the central nervous system, caused by a lyssavirus in the family Rhabdoviridae. It is zoonotic viral disease that can affect all mammals, including humans, cats, dogs, and wildlife and farm animals.
Abdela, N. (Nejash), Balcha, C. (Chernet)   +1 more
core   +2 more sources

Fosl2 Regulates FSH‐Dependent Follicle Maturation Through Feedback Amplification of FSH/FSHR Signaling

Advanced Science, EarlyView.
This study identifies a FOSL2‐driven positive feedback loop that amplifies FSH/FSHR signaling. During FSH‐dependent follicle maturation, FSH induces Fosl2 expression via the cAMP‐PKA‐CREB cascade. FOSL2 in turn binds the promoters of Fshr and estrogen‐biosynthesis genes to enhance their transcription, thereby increasing Fshr mRNA level and amplifying ...
Hongru Shi, Chaoli Chen, Zaohong Ran, Jianning Liao, Zian Wu, Xiaodong Wang, Yongheng Zhao, Wenkai Ke, Bowen Tan, Yun Liu, Youqiang Su, Wei Ren, Xiang Li, Changjiu He   +13 more
wiley   +1 more source

Veterinary Medicine Students’ Perceptions of Hunting and Game Meat: A Cross-Sectional Survey at a Portuguese University

Animals
Background: Veterinarians are pivotal to wildlife health surveillance and game-meat safety, yet these topics receive limited emphasis in many veterinary curricula. Understanding students’ perceptions can inform targeted educational improvements. Methods:
Sara Marques, Ricardo J. Figueiredo, Alexandra Müller, Eduarda Gomes-Neves   +3 more
doaj   +1 more source

Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus

Advanced Science, EarlyView.
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan, Dong Zhou, Ran Shao, Xing Liu, Jin Peng, Yingran Huang, Shuhui Qi, Cankun Xi, Menghang Wang, Bin Sun, Yinglin Qi, Xin Yin   +11 more
wiley   +1 more source

Utilization and acceptance of virtual patients in veterinary basic sciences – the vetVIP-project

GMS Journal for Medical Education, 2017
Context: In medical and veterinary medical education the use of problem-based and cased-based learning has steadily increased over time. At veterinary faculties, this development has mainly been evident in the clinical phase of the veterinary education ...
Kleinsorgen, Christin, Kankofer, Marta, Gradzki, Zbigniew, Mandoki, Mira, Bartha, Tibor, von Köckritz-Blickwede, Maren, Naim, Hassan Y., Beyerbach, Martin, Tipold, Andrea, Ehlers, Jan P.   +9 more
doaj   +1 more source

Nourishing dogs and cats through their twilight years [PDF]

, 2018
Ageing dogs and cats represent a significant proportion of the canine and feline population. Factors attributed to increasing longevity in these species include improved veterinary health care; nutrition; and a healthier lifestyle.
Lumbis, R H
core   +1 more source

Engineering Neuronal Network Connectivity Through Precise and Scalable Electrical Modulation

Advanced Science, EarlyView.
This study presents a scalable all‐electrical method for precise neuronal‐circuit reconfiguration based on high‐density microelectrode arrays. By employing biologically inspired plasticity rules, targeted connectivity changes were successfully induced and quantified across diverse neuronal preparations.
Sreedhar S. Kumar, Yannaël Bossard, Rachel Sava, Tobias Gänswein, Lorenca Sadiraj, Jean‐Samuel Dupré, Manuel Schröter, J. Gray Camp, Fernando Cardes, Julian Bartram, Andreas Hierlemann   +10 more
wiley   +1 more source

Assessing and enhancing quality through outcomes-based continuing professional development (CPD): a review of current practice [PDF]

, 2016
Numerous professional bodies have questioned whether traditional input-based continuing professional development (CPD) schemes are effective at measuring genuine learning and improving practice performance and patient health.
May, S A, Wallace, S
core   +2 more sources