Results 91 to 100 of about 31,788 (164)

Spontaneous Rupture of a Small Chromophobe Renal Cell Carcinoma Presenting as Wunderlich Syndrome

IJU Case Reports, Volume 9, Issue 6, November 2026.
ABSTRACT Introduction Chromophobe renal cell carcinoma rarely causes spontaneous renal hemorrhage and enhances weakly on computed tomography. We report a case in which the tumor was masked by a perirenal hematoma for 11 months. Case Presentation A 46‐year‐old woman presented with spontaneous renal hemorrhage and no visible renal mass.
Naoki Kamimura, Ryohei Yamamoto, Yuya Sekine, Hiromi Sato, Mizuki Kobayashi, Mitsuru Saito, Shintaro Narita, Tomonori Habuchi   +7 more
wiley   +1 more source

Genetics, Pathophysiology, and Current Challenges in Von Hippel–Lindau Disease Therapeutics

Diagnostics
This review article focuses on von Hippel–Lindau (VHL) disease, a rare genetic disorder characterized by the development of tumors and cysts throughout the body. It discusses the following aspects of the disease.
Laura Gómez-Virgilio, Mireya Velazquez-Paniagua, Lucero Cuazozon-Ferrer, Maria-del-Carmen Silva-Lucero, Andres-Ivan Gutierrez-Malacara, Juan-Ramón Padilla-Mendoza, Jessica Borbolla-Vázquez, Job-Alí Díaz-Hernández, Fausto-Alejandro Jiménez-Orozco, Maria-del-Carmen Cardenas-Aguayo   +9 more
doaj   +1 more source

Gastric Cancer: Epidemiology, Risk Factors, Pathogenesis, Clinical Features, Diagnosis, and Management

MedComm, Volume 7, Issue 11, November 2026.
This comprehensive review summarizes gastric cancer epidemiology, multifactorial risk factors (like infectious, dietary, genetic), pathogenesis such as precancerous evolution, molecular alterations, and a focus on the bidirectional interactions between gastric cancer cells and macrophages in the tumor microenvironment.
Yixuan Xin, Xingya Wang, Yangtao Wu, Qian Liu, Qian Ren, Hui Wang, Jingbo Zhai   +6 more
wiley   +1 more source

Disorder of sexual development in a Holstein Friesian calf: Clinical, genetic, MRI and pathological findings

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract A 25‐day‐old Holstein Friesian singleton calf was presented with ambiguous external genitalia suggestive of a disorder of sexual development (DSD). Clinical examination revealed an abnormally positioned urogenital orifice caudal to the mammary complexes, with a palpable tubular structure resembling a hypoplastic penis.
Janice S. M. van der Laan, Joyce M. Parlevliet, Stefanie Veraa, Erik A. W. S. Weerts, Peter R. Hut   +4 more
wiley   +1 more source

Limbal cystotomy by fine needle aspiration of a translucent iris cyst in a horse

Equine Veterinary Education, Volume 38, Issue 11, Page e784-e789, November 2026.
Summary A 4‐year‐old Cremello crossbred mare was referred to the Equine Veterinary Teaching Hospital of Utrecht University for a translucent iris cyst from the dorsal pupillary margin corpora nigra in the right eye. Although noninvasive diode laser treatment is the preferred method of pigmented cyst ablation, two attempts did not result in disruption ...
A. L. Hendrikx, S. Veraa, J. P. A. M. van Loon, H. Hermans, I. J. M. Slenter, E. M. S. Visser   +5 more
wiley   +1 more source

Associations Between Imaging‐Detected Pulp Calcification and Systemic Diseases: A Systematic Review, Thematic Analysis, and Meta‐Analysis

International Endodontic Journal, Volume 59, Issue 11, Page 2283-2302, November 2026.
ABSTRACT Background Pulp calcification (PC) is a common imaging finding traditionally attributed to local factors or ageing. However, increasing evidence suggests that it may be associated with broader systemic biological disturbances. Clarifying this association may help determine whether dental pulp findings contribute to the interpretation of ...
José Evando da Silva‐Filho, Paula Maria da Costa Torres, Eduardo Diogo Gurgel‐Filho   +2 more
wiley   +1 more source

Limiting Trial‐and‐Error: Linker‐Based 2D Descriptor Analysis to Support Very Early Proteolysis‐Targeting Chimeras Design

ChemMedChem, Volume 21, Issue 19, 14 October 2026.
Can simple linker descriptors guide PROTAC design? Analysis of matched CRBN‐ and VHL‐recruiting degraders shows that basic 2D linker properties may capture trends linked to degradation efficiency, in vitro ADME and physicochemical properties. A practical approach to reduce trial‐and‐error in early targeted protein degradation programs. Targeted protein
Giulia Apprato, Serena Traversa, Giulia Caron, Giuseppe Ermondi   +3 more
wiley   +1 more source

Sodium-Glucose Cotransporter 2-Mediated Glucose Uptake Contributes to Glycogen Accumulation in Clear Cell Renal Cell Carcinoma: Implications for Clear Cell Morphology and Potential Therapeutic Relevance. [PDF]

Int J Mol Sci
Nagata Y, Tomisaki I, Matsukawa T, Quynh NT, Tsubonuma Y, Sugita Y, Nawata A, Kokubu K, Baba R, Morimoto H, Ogawa K, Wada K, Fujimoto N.   +12 more
europepmc   +1 more source

Antiangiogenic Drug Testing Using Proangiogenic and Hypoxia Zebrafish Model. [PDF]

Bio Protoc
Vinoth S, Santhakumar K.
europepmc   +1 more source

Intradural cauda equina hemangioblastomas: Surgical management and long-term outcomes at a von Hippel-Lindau referral center. [PDF]

Brain Spine
Doria-Medina R, Neidert N, Hohenhaus M, Gizaw CJ, Rhein K, Ganner A, Hohenhaus R, Beck J, Klingler JH.   +8 more
europepmc   +1 more source