Results 31 to 40 of about 2,389,803 (336)

A Review of Methods to Determine Viability, Vitality, and Metabolic Rates in Microbiology

open access: yesFrontiers in Microbiology, 2020
Viability and metabolic assays are commonly used as proxies to assess the overall metabolism of microorganisms. The variety of these assays combined with little information provided by some assay kits or online protocols often leads to mistakes or poor ...
Olivier Braissant   +3 more
doaj   +1 more source

Asiaticoside reverses M2 phenotype macrophage polarization-evoked osteosarcoma cell malignant behaviour by TRAF6/NF-κB inhibition

open access: yesPharmaceutical Biology, 2022
Context M2 phenotype macrophage polarization is an attractive target for therapeutic intervention. Asiaticoside (ATS) has multiple pharmacological functions.Objective This study investigates the effect of ATS on M2 phenotype macrophage polarization in ...
Dang-ke Li, Guang-hui Wang
doaj   +1 more source

Measurement and models accounting for cell death capture hidden variation in compound response. [PDF]

open access: yes, 2020
Cancer cell sensitivity or resistance is almost universally quantified through a direct or surrogate measure of cell number. However, compound responses can occur through many distinct phenotypic outcomes, including changes in cell growth, apoptosis, and
Bae, Song Yi   +5 more
core   +1 more source

DAO Research Trends: Reflections and Learnings from the First European DAO Workshop (DAWO)

open access: yesApplied Sciences
Decentralized Autonomous Organizations (DAOs) represent a transformative shift in organizational structures, combining decentralized governance with blockchain-based smart contracts.
Michael Lustenberger   +4 more
doaj   +1 more source

Predicting Neonatal Skin Injury: The First Step to Reducing Skin Injuries in Neonates

open access: yesHealth Services Insights, 2019
Background: Skin injuries remain common in neonates admitted to neonatal intensive care units. While predicting neonates at risk of skin injury may assist in reducing the incidence of injury, currently there is limited evidence on which tool may be ...
Margaret Broom   +2 more
doaj   +1 more source

DAO as digital governance tool for collaborative housing

open access: yesFrontiers in Blockchain
This paper explores the promise of decentralized autonomous organizations (DAOs) as a digital governance tool for collaborative housing initiatives. Based on existing literature around the collaborative housing initiative no1s1, we explore the research ...
Michael Lustenberger   +3 more
doaj   +1 more source

A rhodanine agent active against non-replicating intracellular Mycobacterium avium subspecies paratuberculosis. [PDF]

open access: yes, 2009
BACKGROUND: Antibiotic therapy targeting chronic mycobacterial disease is often ineffective due to problems with the emergence of drug resistance and non-replicating persistent intracellular antibiotic resistant phenotypes.
Bull, TJ   +3 more
core   +3 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Blockchain-based voluntary carbon market: strategic insights into network structure

open access: yesFrontiers in Blockchain
This research examines the structure of blockchain-based voluntary carbon market (VCM) and the factors shaping their formation. Conducted as part of the 2023–2025 Innosuisse project 104.664 IP-EE, it aims to provide insights to support participants in ...
Eleonóra Bassi   +2 more
doaj   +1 more source

The Bioactive Potential of Functional Products and Bioavailability of Phenolic Compounds

open access: yesFoods, 2020
The expression of bioactivity depends on the assimilation of different classes of natural substances (e.g., phenolic compounds) in vivo. Six functional extracts (Aspalathus linearis, leaves; Paullinia cupana, seeds; Aristotelia chilensis, berries; Ilex ...
Cristina Monica Dabulici   +2 more
doaj   +1 more source

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