Results 31 to 40 of about 573,006 (357)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Variable friction secondary seal for face seals [PDF]

open access: yes, 1986
Vibration and stability of a primary seal ring is controlled by a secondary seal system. An inflatable bladder which forms a portion of the secondary seal varies the damping applied to this seal ring.
Dirusso, E.
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Hybrid iterative learning control of a flexible manipulator [PDF]

open access: yes, 2004
This paper presents an investigation into the development of a hybrid control scheme with iterative learning for input tracking and end-point vibration suppression of a flexible manipulator system.
Mailah, M   +3 more
core  

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Influence of plasma-enhanced combustion on RBCC engine using URANS

open access: yesScientific Reports
The rocket-based combined-cycle (RBCC) engine is regarded as one of the most viable propulsion systems for single-stage-to-orbit launch vehicles. Because of the relatively low total temperature of the incoming flow, it is difficult to maintain sustained ...
Wei-Rui Zhang   +4 more
doaj   +1 more source

Design and Experimental Research of a Rotary Micro-Actuator Based on a Shearing Piezoelectric Stack

open access: yesMicromachines, 2019
The working principle of a rotating micro-actuator based on a piezoelectric stack was theoretically analyzed and experimentally verified. The actuator is compact in structure, and the key component is the shearing piezoelectric stack.
Hehe Huang, Longfei Wang, Ying Wu
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Structural Parameter Optimization of a Tubular Permanent-Magnet Linear Machine for Regenerative Suspension

open access: yesShock and Vibration, 2019
The regenerative suspension can effectively recover the vibration potential energy of the vehicle suspension, thus has broad prospects in application. In this paper, a tubular permanent-magnet linear motor (TPMLM) with the Halbach array magnetic pole is ...
Dongsheng Lu   +3 more
doaj   +1 more source

A soft sandwich structure enables voltage-induced actuation of liquid metal embedded elastomers

open access: yesAIP Advances, 2020
Dispersing liquid metal droplets in a soft elastomer matrix yields a composite, called liquid metal embedded elastomer (LMEE), with less modified stiffness but noticeably increased relative permittivity.
Yin Wang   +4 more
doaj   +1 more source

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