Results 61 to 70 of about 2,440 (209)

The development of biomolecular Raman optical activity spectroscopy [PDF]

, 2015
Following its first observation over 40 years ago, Raman optical activity (ROA), which may be measured as a small difference in the intensity of vibrational Raman scattering from chiral molecules in right- and left-circularly polarized incident light or,
Barron, Laurence D.
core   +1 more source

Multispectral Chiral Quasi‐Bound States in the Continuum Enabled Microfluidics for High‐Throughput Molecular Screening and Quantification

Advanced Science, Volume 12, Issue 47, December 18, 2025.
A microfluidics‐integrated chiral quasi‐BIC metachip is developed that generates strong broadband CD from 0.5–2.0 THz in aqueous environments. A UMAP algorithm processes the resulting multidimensional CD features for simultaneous biomolecular conformation identification and concentration quantification (0.05–0.3 mg dL−1).
Xinyue Liang, Zihan Zhao, Xiaocong Tang, Haiyue Yang, Lanju Liang, Meng Zhao, Cong Wang, Lei Wang, Xumin Ding   +8 more
wiley   +1 more source

Multichannel array detection of vibrational optical activity free-induction-decay

Journal of Analytical Science and Technology, 2010
By introducing a multichannel array detector to vibrational optical activity free-induction-decay (VOA FID) measurement spectrometer, we successfully measured the vibrational circular dichroism (VCD) spectrum of (1S)-β-pinene.
Hanju Rhee, Seong-Soo Kim, Minhaeng Cho
doaj  

On the Absolute Stereochemistry of Tolterodine: A Circular Dichroism Study

Pharmaceuticals, 2019
Tolterodine (1) is a potent muscarinic receptor antagonist used in the treatment of overactive urinary bladder (OAB) syndrome. Tolterodine is chiral and it was patented, and is currently marketed, as the l-tartrate salt of the (R)-enantiomer.
Marcin Górecki, Valerio Zullo, Anna Iuliano, Gennaro Pescitelli   +3 more
doaj   +1 more source

Chiral Lanthanide Complexes with l- and d-Alanine: An X-ray and Vibrational Circular Dichroism Study

Molecules, 2020
A whole series of [Ln(H2O)4(Ala)2]26+ dimeric cationic lanthanide complexes with both l- and d-alanine enantiomers was synthesized. The single-crystal X-ray diffraction at 100 and 292 K shows the formation of two types of dimers (I and II) in crystals ...
Krzysztof Lyczko, Joanna E. Rode, Jan Cz. Dobrowolski   +2 more
doaj   +1 more source

Synthesis and Characterization of (R)‐ and (S)‐1,1′‐Bi‐2‐Naphtholato Coordinated Gallium(III) Porphyrins and Their Chiroptical Properties

European Journal of Inorganic Chemistry, Volume 28, Issue 32, November 10, 2025.
Gallium porphyrins bearing chiral bi‐2‐naphtholato ligands are synthesized and characterized. Single‐crystal X‐ray diffraction and various spectroscopic analyses confirmed their structures. Circular dichroism spectroscopy revealed a Cotton effect corresponding to the absorption band of the achiral porphyrin core.
Shafikul Islam, Md Jadu Mia, Daiki Tauchi, Masashi Hasegawa, Marco Fusè, Giuseppe Mazzeo, Giovanna Longhi, Sergio Abbate, Ken‐ichi Yamashita, Ken‐ichi Sugiura   +9 more
wiley   +1 more source

Asymmetric Synthesis of Spirooxindoles via Nucleophilic Epoxidation Promoted by Bifunctional Organocatalysts [PDF]

, 2018
Taking into account the postulated reaction mechanism for the organocatalytic epoxidation of electron-poor olefins developed by our laboratory, we have investigated the key factors able to positively influence the H-bond network installed inside the ...
Abbate, Sergio, Gasperi, Tecla, Longhi, Giovanna, Lupattelli, Paolo, Mazzeo, Giuseppe, Mazziotta, Andrea, Miceli, Martina, Palumbo, Chiara, Roma, Elia, Tosi, Eleonora   +9 more
core   +2 more sources

Terahertz Raman Optical Activity Reveals Emergent Supramolecular Chirality in Mononucleotide G‐quadruplexes

Chemistry–Methods, Volume 5, Issue 11, November 2025.
Self‐assembly of guanosine‐5′‐monophosphate into G‐quadruplexes induces a cation‐specific (sodium vs. potassium), intense terahertz Raman optical activity signal. The supramolecular helical arrangement gives rise to a distinct chiral vibrational signature in the low‐frequency region.
Štěpán Jílek, Josef Kapitán, Václav Profant   +2 more
wiley   +1 more source

Shining Light at Working Interfaces and Chiral Nanoparticles

CHIMIA, 2011
In this article we present an overview of our recent research in the fields of in situ spectroscopy, nanomaterials and chirality. Our research focuses around the spectroscopic investigation of chemical reactions taking place at solid–liquid ...
Thomas Bürgi
doaj   +1 more source

Oxygenated Acyclic Diterpenes with Anticancer Activity from the Irish Brown Seaweed Bifurcaria bifurcata

Marine Drugs, 2020
Brown alga Bifurcaria bifurcata is a prolific source of bioactive acyclic (linear) diterpenes with high structural diversity. In the continuation of our investigations on Irish brown algae, we undertook an in-depth chemical study on the n-hexanes and ...
Vangelis Smyrniotopoulos, Christian Merten, Daria Firsova, Howard Fearnhead, Deniz Tasdemir   +4 more
doaj   +1 more source