Results 61 to 70 of about 256,210 (317)

Engineering Bacteria as Living Therapeutics in Cancer Therapy

Advanced Science, EarlyView.
Through synthetic biology approaches, natural bacteria can be genetically programmed into multifunctional living therapeutics. These engineered bacteria are capable of secreting anti‐tumor factors, displaying tumor‐associated antigens on their surface, or undergoing programmed self‐lysis to release therapeutic cargo.
Jiangfeng Chen, Jiaqi Chen, Yixuan Chen, Wenxuan Yuan, Jiao Zhang, Guoqing Wang, Zhuojun Dai   +6 more
wiley   +1 more source

Directed evolution of Vibrio fischeri LuxR for improved response to butanoyl-homoserine lactone [PDF]

, 2007
LuxR is the 3-oxohexanoyl-homoserine lactone (3OC6HSL) dependent transcriptional activator of the prototypical acyl-homoserine lactone (AHL) quorum sensing system of Vibrio fischeri.
Arnold, Frances H., Hauer, Bernhard, Hawkins, Andrew C., Leadbetter, Jared R., Stuermer, Rainer   +4 more
core   +3 more sources

Existence and characteristics of Vibrio species isolated from fish marketed in Sohag governorate, Egypt and their control by essential oils

SVU-International Journal of Veterinary Sciences, 2023
The aims of this study were isolation and characterization of Vibrio species isolated from fish meat. A total 100 fish samples including chilled Tilapia nilotica, chilled cat-fish (Clarias gariepinus), frozen mackerel and frozen shrimp were collected ...
Ola Yousef, Hesham Abdel-Moez Ismail , Mohamed Abdelfattah Maky   +2 more
doaj   +1 more source

Material‐to‐Application Integration: Rapid Fabrication of Field‐Deployable Hydrogel‐SiO2 DNA Separator for Low‐Resource Point‐of‐Care Diagnostics

Advanced Science, EarlyView.
A rapidly fabricated hydrogel‐SiO2 composite enables ultralow‐cost, equipment‐minimized DNA extraction, outperforming commercial kits. Hierarchical microstructures enhance hydrophobic/salt‐bridge‐driven adsorption. Integrated with visual LAMP, this field‐deployable system detects Vibrio parahaemolyticus at 10 CFU mL−1 in <40 min, offering ...
Peipei Li, Xinrong Li, Haojie Wu, Dongmei Yue, Yubo Shang, Shan Gao, Bai Wang, Xiaobin Jiang, Jingwei Jiang, Zunchun Zhou   +9 more
wiley   +1 more source

Comparative Microbial Dynamics in Crassostrea virginica and Crassostrea ariakensis [PDF]

, 2006
Considerations to introduce the Suminoe or Asian oyster Crassostrea ariakensis along the East Coast have raised many questions regarding ecology, economics, and human health.
Bean, Tanya J., Fowler, Patricia K., Morris, Jr., James A., Noble, Rachel T.   +3 more
core  

Balancing Cell Growth and Product Synthesis for Efficient Microbial Cell Factories

Advanced Science, EarlyView.
This review presents state‐of‐the‐art metabolic engineering strategies to balance microbial cell growth and product synthesis in biorefineries. It surveys pathway engineering, dynamic genetic circuits, orthogonal control systems, synthetic microbial consortia, and fermentation optimization, alongside integrative modeling approaches.
Linxia Liu, Dongqin Ding, Huiying Wang, Xinyi Ren, Sang Yup Lee, Dawei Zhang   +5 more
wiley   +1 more source

Resistance to Antimicrobial Peptides in Vibrios

Antibiotics, 2014
Vibrios are associated with a broad diversity of hosts that produce antimicrobial peptides (AMPs) as part of their defense against microbial infections. In particular, vibrios colonize epithelia, which function as protective barriers and express AMPs as ...
Delphine Destoumieux-Garzón, Marylise Duperthuy, Audrey Sophie Vanhove, Paulina Schmitt, Sun Nyunt Wai   +4 more
doaj   +1 more source

Report on Vibrio Species Contamination in Shrimp From the Coast of Pangandaran, West Java, Indonesia. [PDF]

Environ Microbiol Rep
Shrimp samples from Pangandaran, Indonesia, revealed contamination by Vibrio parahaemolyticus and Vibrio alginolyticus. Toxin gene screening showed the presence of toxR but the absence of highly pathogenic markers (tdh, trh, pirA, pirB). These findings highlight infection risks and the need for improved biosecurity in shrimp aquaculture.
Herawati T, Rahayu I, Aisyah A, Agung MUK, Pasaribu B, Nurhayati A, Ghazali A, Grandiosa R, Faddilah TN, Kamiswara R.   +9 more
europepmc   +2 more sources

Permeability and Enterotoxic Factors of Nonagglutinable Vibrios Vibrio alcaligenes and Vibrio parahaemolyticus [PDF]

Applied Microbiology, 1971
Enterotoxic factor (EF) was present and could be developed in nonagglutinable vibrios, but not the permeability factor (PF). Presence of PF without EF in Vibrio parahaemolyticus is significant. Both EF and PF were absent in V. alcaligenes.
Sujit K. Bhattacharya, A. K. Bose, Amit Ghosh   +2 more
openaire   +3 more sources

An Engineered Probiotic Consortium Based on Quorum‐Sensing for Colorectal Cancer Immunotherapy

Advanced Science, EarlyView.
This work develops an engineered probiotic consortium sensing pH, hypoxia, and lactate in the tumor microenvironment. It releases a lactate‐depleting enzyme (LdhA) and a PD‐L1 nanobody. In humanized mouse models (MC38 and HT‐29 tumors), it achieves durable oscillations, suppresses tumors, activates CD8+, CD4+, IFN‐γ+ T cells, and reduces Foxp3 ...
Yufei Guo, Mengxue Gao, Lina Wang, Haibin Yuan, Jianan Yin, Jiahao Wu, Xinran Gao, Zhixin Zhu, Yan Zhang, Zichen Wang, He Huang, Guangbo Kang   +11 more
wiley   +1 more source