Results 111 to 120 of about 582,403 (259)

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

2009WE7L2E_003Ruolo della sfingosina-1-fosfato (S1P) nell'infiammazione polmonare e nel rimodellamento delle vie aeree: valutazioni molecolari e funzionali

open access: yes, 2011
cellulari fisio-patologiche inducendo apoptosi e sopravvivenza cellulare, alterazioni nella permeabilità vascolare, attivazione dei mastociti e modulazione dell'attività muscolatura liscia delle vie aeree. S1P è sintetizzata da 2 isoforme enzimatiche
SORRENTINO, RAFFAELLA
core  

Effect of terahertz irradiation on DNA damage repair in living cells

open access: yesFEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno   +3 more
wiley   +1 more source

Le Répertoire de la vie française en Amérique

open access: yes, 1991
1991
Conseil de la vie française en Amérique
core   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Mutuelle Générale Française Vie

open access: yes
Modelo de portada de póliza de seguro de la MUTUELLE GENERALE FRANÇAISE VIE. Aparece con el nº general 173255, y el nº de delegación es el 656. En esta portada aparece, en la parte superior, el texto en latín: "mutua fide cenomani satum ubique floreat ...
Mutuelle Générale Française Vie
core  

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Qualité de vie: Santé, Ecologie, Environnement

open access: yes, 1997
International audienceCan we define the quality of life? Manufacturers in the pursuit of excellence and the best rates of profitability characterize quality as the ability of a product or service to meet the expressed or latent needs of users. To achieve
Vernazza-Licht, Nicole, Bley, Daniel
core   +2 more sources

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

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