Results 111 to 120 of about 414,171 (309)
Handicap, handicaps ? Vie normale, vie parfaite, vie handicapée
Calenda, 2012 Le département de recherche « Éthique biomédicale » du Collège des Bernardins étudie les enjeux anthropologiques et éthiques de la recherche médicale et de ses applications. Son travail de recherche est mené sous forme de séminaires mensuels co-dirigés par un universitaire et un professeur de théologie avec la participation de chercheurs, philosophes ...
openaire +1 more source
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
Mais pourquoi "la vie" d'Adèle ? (Sur La vie d'Adèle d'A. Kechiche) [PDF]
, 2013 Oui, pourquoi la « vie » d’Adèle ? À l’évidence, Kechiche ne nous en montre qu’une tranche, de la fin de ses années de lycée à ses premiers pas d’institutrice maternelle. Pourquoi alors la vie d’Adèle, et pas : l’adolescence d’Adèle, la passion d’Adèle,
Janvier, Antoine, Hagelstein, Maud
core
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Modulating satiety with neuro-music: a frequency-specific acoustic approach to appetite control
Frontiers in Human NeuroscienceIntroductionGlobal obesity rates are rising, necessitating innovative interventions for appetite control. This study investigated whether subjective satiety—referred to as “hunger stress”—can be modulated using frequency-specific acoustic stimulation ...
Ming Chang +12 more
doaj +1 more source