Results 91 to 100 of about 1,314,530 (315)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Rocas utilizables en la fabricación de refractarios de sílice

open access: yesMateriales de Construccion, 1949
No ...
G. Vié
doaj   +1 more source

The Micro Dynamic of Exporting-Evidence from French Firms [PDF]

open access: yes
This paper describes the dynamics of rms' exports to dierent countries. Using a panel of almost 19,000 French exporters, we dene an export-relation as an observed positive export ow from a French rm to a destination. We establish the following facts: 1.
Harald Fadinger   +2 more
core  

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

A dynamic pricipal-agent problem as a feedback Stackelberg differentioal game [PDF]

open access: yes
We consider situations in which a principal tries to induce an agent to spend e®ort on accumulating a state variable that a®ects the well-being of both parties.
Gerhard Sorger, Ngo Van Long
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Handicap, handicaps ? Vie normale, vie parfaite, vie handicapée

open access: yesCalenda, 2012
Le département de recherche « Éthique biomédicale » du Collège des Bernardins étudie les enjeux anthropologiques et éthiques de la recherche médicale et de ses applications. Son travail de recherche est mené sous forme de séminaires mensuels co-dirigés par un universitaire et un professeur de théologie avec la participation de chercheurs, philosophes ...
openaire   +1 more source

An explanation for the inverted-U relationship between competition and innovation [PDF]

open access: yes
The Dixit-Stiglitz model is extended by the possibility for rms to un- dertake process innovation. The model can provide a new explanation to describe the relationship that research activity of rms is positively corre- lated with product market ...
Ferdinand Rauch
core  

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Democracy and Economic Development [PDF]

open access: yes
With the goal of freeing the world from poverty, some Western authorities have consistently insisted on promoting democracy in totalitarian states in the past decades.
Chittawan Chanagul
core  

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