Results 71 to 80 of about 414,171 (309)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Las obras de acondicionamiento del Salto del Mont-Cenis
Informes de la Construccion, 1969 La capacidad de la nueva presa del Mont-Cenis ha aumentado con estas obras desde 32 hasta 320 millones de m3, permitiendo el abastecimiento de una energía potencial de 650.000 millones de Mp x m.
Georges Vié
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Perforación de galerías sin empleo de explosivos
Informes de la Construccion, 1967 La perforación de galerías presenta distintos problemas según la naturaleza del terreno y la ubicación de la obra. La imposibilidad de emplear tiros de mina en perforaciones bajo zonas urbanas, da lugar al empleo cada vez más frecuente de la maquinaria ...
Georges Vié
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
, 2008 H29 is a private gallery in Brussels, Belgium. This exhibition united 50 artists from Belgium, several European countries, the USA and Australia to present 'LA VIE EN ROND'
Jenkins, Kyle
core
Métodos modernos de excavación de galerías y túneles
Informes de la Construccion, 1967 El avance extraordinario registrado en los últimos años en el campo de las obras públicas se debe, fundamentalmente, al empleo masivo de maquinaria auxiliar en cualquier tajo de una obra.
Georges Vié
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
2009WE7L2E_003Ruolo della sfingosina-1-fosfato (S1P) nell'infiammazione polmonare e nel rimodellamento delle vie aeree: valutazioni molecolari e funzionali [PDF]
, 2011 cellulari fisio-patologiche inducendo apoptosi e sopravvivenza cellulare, alterazioni nella permeabilità vascolare, attivazione dei mastociti e modulazione dell'attività muscolatura liscia delle vie aeree. S1P è sintetizzata da 2 isoforme enzimatiche
SORRENTINO, RAFFAELLA
core
Perforación y revestimiento de la galería de Laval de Cère II (Francia)
Informes de la Construccion, 1966 El aprovechamiento hidroeléctrico de Cère II constituye un complejo importante que explota EDF. Situado en el macizo central, montañoso, presenta las características generales del tipo, esto es, aquí las galerías son la parte más importante.
Georges Vié
doaj +1 more source