Results 41 to 50 of about 582,403 (259)
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
El motivo principal para la construcción de esta autopista ha sido la saturación de la Carretera Nacional 10, incapaz ya de absorber el tráfico actual entre Burdeos y la Frontera del Bidasoa, especialmente en los períodos de verano.
G. Vie
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Aplicaciones de láminas flexibles y estancas en obras públicas
En materia de construcción, el progreso de la técnica permite la utilización y puesta en obra de los materiales más insospechados, destacando, en este sentido, las aplicaciones de materiales recientes, tales como los plásticos en láminas, fieltros ...
George Vié
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Perforaciones de los grandes subterráneos y los métodos y máquinas modernos
La perforación de los grandes subterráneos, bien sea para trabajos de minas o de obras públicas, debe acometerse bajo unos patrones característicos en todas estas grandes obras, como son: la seguridad, resistencia, economía, etc.
G. Vié
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Le Japon pendant la Première Guerre mondiale : fonctionnement de l’État et politique extérieure
Unprecedented in its scope, the First World War was also unique in the Western efforts it triggered to find the “meaning or direction of history”, a desire to see war as the secret to a peaceful world.
Michel Vié
doaj +1 more source
The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
El «mastic» bituminoso en las obras hidráulicas y marítimas
En este trabajo, el autor estudia, y pone de relieve prácticamente, el amplio campo de aplicaciones que se le ofrecen a los productos mixtos, conocidos con el nombre de mastics, en las construcciones hidráulicas y marítimas.
Georges Vié
doaj +1 more source

