Results 91 to 100 of about 14,898 (265)

Immediate Therapeutic Response to Vigabatrin in Lissencephaly‐Related Epileptic Spasms due to TUBA1A R402H Variant

open access: yes
American Journal of Medical Genetics Part A, Volume 197, Issue 7, July 2025.
Toru Nagata   +6 more
wiley   +1 more source

Response to vigabatrin in relation to seizure type. [PDF]

open access: bronze, 1989
Roberto Michelucci, C. A. Tassinari
openalex   +1 more source

Vigabatrin Retinal Toxicity First Detected with Electroretinographic Changes: A Case Report.

open access: yesJournal of Clinical & Experimental Ophthalmology, 2014
Vigabatrin is an effective antiepileptic drug (AED) typically used in the treatment of refractory partial seizures and infantile spasms. Its use, however, is limited due to the concern of retinal toxicity and subsequent visual field defects.
D. Barrett   +3 more
semanticscholar   +1 more source

Ketamine abuse and apoptosis in the cortex in monkeys and mice [PDF]

open access: yes, 2008
International Journal of Neuropsychopharmacology, 2008, v. 11, suppl. 1, p. 236-237, abstract no.
Lam, WP   +4 more
core  

Chronic Toxicity Studies with Vigabatrin, A GABA-Transaminase Inhibitor [PDF]

open access: bronze, 1990
John P. Gibson   +5 more
openalex   +1 more source

Vigabatrin Inhibits Seizures and mTOR Pathway Activation in a Mouse Model of Tuberous Sclerosis Complex

open access: yesPLoS ONE, 2013
Epilepsy is a common neurological disorder and cause of significant morbidity and mortality. Although antiseizure medication is the first-line treatment for epilepsy, currently available medications are ineffective in a significant percentage of patients
Bo Zhang   +3 more
semanticscholar   +1 more source

Evaluating Risks for Vigabatrin Treatment [PDF]

open access: yesEpilepsy Currents, 2009
Approximately 30 to 40 percent of adults with epilepsy treated chronically with vigabatrin develop concentric visual field constrictions. These deficits are generally mild and asymptomatic, but are usually irreversible, so risks and benefits for vigabatrin treatment must be carefully reviewed.
openaire   +2 more sources

Intestinal absorption of the antiepileptic drug substance vigabatrin is altered by infant formula in vitro and in vivo.

open access: yesPharmacology Research & Perspectives, 2014
Vigabatrin is an antiepileptic drug substance mainly used in pediatric treatment of infantile spasms. The main source of nutrition for infants is breast milk and/or infant formula.
M. K. Nøhr   +5 more
semanticscholar   +1 more source

Study of visual field defects in patients with epilepsy receiving Vigabatrin [PDF]

open access: yes, 2009
Vigabatrin, a GABA (γ-aminobutyric acid) agonist is a drug widely prescribed in Europe and Asia between 1989 and 1997 for drug resistant, partial epilepsy and has been associated with visual field defects.
Gonzalez, Pedro Antonio
core   +1 more source

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