Results 151 to 160 of about 113,790 (365)
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit +19 more
wiley +1 more source
Probit regression to estimate the physiological potential of hybrid maize seed
Journal of Seed ScienceThis work was carried out to study the physiological potential of artificially aged seed lots of maize. The specific aim of this study was to fit a simplified equation from Andreoli, , and present a methodology using probit regression analysis, given by ...
Sebastião Gazola +5 more
doaj +1 more source
Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source
Accelerated aging and seedling field emergence in soybean
Scientia Agricola, 2004 Information regarding the relationship between laboratory seed vigor testing and seedling field emergence is very important to estimate seed performance after sowing and help producers adopt the best procedures to improve stand establishment.
Reynaldo Melo Torres +2 more
doaj
, 2017 {"references": ["Gmelin JF (1788) Caroli a Linne, Systema naturae per regna tria naturae: secundum classes, ordines, genera, species, cum characteribus, differentiis, synonymis, locis. Tomus I. Pars I. Impensis Beer, Georg Emanuel, Lipsiae, 500 pp.", "Medway L, Marshall AG (1975) Terrestrial vertebrates of the New Hebrides: origin and distribution ...
Andersen, Michael J. +3 more
openaire +2 more sources
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
Molecular Oncology, EarlyView.In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
, 2009 Explorers have made breakthroughs in many fields of astrophysics. The science from both these missions contributed to three Nobel Prizes - Giacconi (2002), Mather, and Smoot (2006). Explorers have: marked the definitive beginning of precision cosmology, discovered that short gamma-ray bursts are caused by compact star mergers and have measured ...
Elvis, Martin +49 more
openaire +2 more sources
Understanding and measuring mechanical signals in the tumor stroma
FEBS Open Bio, EarlyView.This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz +3 more
wiley +1 more source