Results 71 to 80 of about 56,724 (289)

Evaluación del vigor en el cultivo de jamaica (Hibiscus sabdariffa L.) utilizando rizobacterias con fines de fitorremediación bajo condiciones de estrés ocasionado por sulfato de cobre (CuSo4)

open access: diamond, 2022
Abdul Khalil Gardezi   +9 more
openalex   +2 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Non-destructive detection strategy of maize seed vigor based on seed phenotyping and the potential for accelerating breeding

open access: yesJournal of Advanced Research
Introduction: Seeds are fundamental to agricultural production, and their vigor affects seedling quality, quantity, and crop yield. Accurate vigor assessment methods are crucial for agricultural productivity.
Keling Tu   +9 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Seed germination responses of sorghum lines and cultivars under salinity stress conditions [PDF]

open access: yesعلوم و فناوری بذر ایران, 2017
To evaluate the effect of salinity stress on germination indices of sorghum, this experiment was conducted using a factorial arrangement based on a completely randomized design (CRD) with three replications at Cereal laboratory of College of Agriculture,
E. Shakeri   +3 more
doaj  

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Quality of soybean seeds with high mechanical damage index after processing and storage

open access: yesRevista Brasileira de Engenharia Agrícola e Ambiental
This study aimed to evaluate the quality of soybean seeds with high level of mechanical damages from different processing stages and stored with and without fungicide treatment.
José M. G. Neve   +5 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

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