Results 71 to 80 of about 113,790 (365)
Control of movement vigor and decision making during foraging
Proceedings of the National Academy of Sciences of the United States of America, 2018 Significance How long should one stay and accumulate reward, and then, how fast should one travel to the next reward site? Marginal value theorem describes the decision-making process: the brain compares the immediate rate of harvest with its global ...
Tehrim Yoon +3 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
Reward Prediction Error Modulates Saccade Vigor
Journal of Neuroscience, 2019 Movement vigor, defined as the reciprocal of the latency from availability of reward to its acquisition, changes with reward magnitude: movements exhibit shorter reaction time and increased velocity when they are directed toward more rewarding stimuli ...
Ehsan Sedaghat-Nejad +2 more
semanticscholar +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Vigorous convection in porous media [PDF]
Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2020 The problem of convection in a fluid-saturated porous medium is reviewed with a focus on ‘vigorous’ convective flow, when the driving buoyancy forces are large relative to any dissipative forces in the system. This limit of strong convection is applicable in numerous settings in geophysics and beyond, including geothermal circulation ...
openaire +4 more sources
Rapid evaluation of seed vigor by the absolute content of protein in seed within the same crop
Scientific Reports, 2018 Seed vigor, an important index of seed quality, determines the potential for rapid and uniform emergence of plants. The objective of this study was to explore a rapid method for evaluating seed vigor.
Daxing Wen +5 more
semanticscholar +1 more source
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum
FEBS Letters, EarlyView.In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti +3 more
wiley +1 more source
, 2018 Published as part of Somenzari, Marina, Amaral, Priscilla Prudente do, Cueto, Víctor R., Guaraldo, André de Camargo, Jahn, Alex E., Lima, Diego Mendes, Lima, Pedro Cerqueira, Lugarini, Camile, Machado, Caio Graco, Martinez, Jaime, Nascimento, João Luiz Xavier do, Pacheco, José Fernando, Paludo, Danielle, Prestes, Nêmora Pauletti, Serafini, Patrícia ...
Somenzari, Marina +20 more
openaire +3 more sources
Impacts of vigorous and non-vigorous activity on daily energy expenditure [PDF]
Proceedings of the Nutrition Society, 2003 Activity intensity is a potential determinant of activity-induced energy expenditure. Tri-axial accelerometery is the most objective measurement technique for the assessment of activity intensity, in combination with doubly-labelled water for the measurement of energy expenditure under free-living conditions.
openaire +4 more sources
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source