Results 51 to 60 of about 21,278 (265)

Genomic Regions for Embryo Size and Early Vigour in Multiple Wheat (Triticum aestivum L.) Populations

Agronomy, 2015
Greater early vigour has potential for increasing biomass and grain yields of wheat crops in Mediterranean-type environments. Embryo size is an important determinant of early vigour in barley and likely to contribute to greater vigour in wheat. Little is
Chris Moore, Greg Rebetzke
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Sex Differences in High-Cost Users of Healthcare for Atrial Fibrillation

CJC Open
Background: Healthcare resource use for atrial fibrillation (AF) is high, but it may not be equivalent across all patients. We examined whether sex differences exist for AF high-cost users (HCUs), who account for the top 10% of total acute care costs ...
Roopinder K. Sandhu, MD, MPH, Hena Qureshi, MSc, Heather Halperin, BSc, Douglas C. Dover, PhD, Nathan Klassen, MA, Nathaniel M. Hawkins, MD, Jason G. Andrade, MD, Padma Kaul, PhD   +7 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Influência das embalagens e condições de armazenamento no vigor de sementes de gergelim Influence of packing and storage conditions on the vigor of sesame seeds

Revista Brasileira de Engenharia Agrícola e Ambiental, 2003
No Brasil, os problemas de armazenamento são sérios e as perdas, nessa fase, consideráveis. A qualidade fisiológica das sementes enquanto armazenadas deve ser avaliada, sob pena de não se obter a produtividade desejada. O presente estudo foi desenvolvido
Márcia R. de Q. A. Azevedo, Josivanda P. G. de Gouveia, Dilma M. de M. Trovão, Vicente de P. Queiroga   +3 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Seed size and its effects on the physiological quality of produced seeds [PDF]

Revista Ciência Agronômica
The physiological quality of soya bean seeds is a determining factor in establishing the crop in the field. The aim of the present study was to evaluate the physiological quality of soya bean seeds produced by plants grown from seeds of different sizes ...
Alcimar Spindola Mazon, Luis Henrique Konzen, Danielle Brandstetter Rodrigues, Geri Eduardo Meneghello, Lílian Vanussa Madruga de Tunes   +4 more
doaj   +1 more source