pharma-kritik, 2008 Mit Vildagliptin steht - neben Sitagliptin - ein weiterer sogen. DPP-4-Hemmer zur Verfügung. Das Medikament senkt das HbA1c weniger stark als Metformin. Daten zu klinisch relevanten Endpunkten liegen noch keine vor.
Urspeter Masche
openaire +2 more sources
The Influence of Excipients’ Chemical Nature on the Degradation of Metformin and Vildagliptin [PDF]
Kemija u IndustrijiThe influence of the chemical nature of excipients (magnesium stearate, povidone, microcrystalline cellulose, lactose, crospovidone, and talc) on the degradation of metformin and vildagliptin was tested by forced degradation, using acid hydrolysis, base ...
Amra Demirović +2 more
doaj +2 more sources
Indian Journal of Endocrinology and Metabolism, 2012 Objective: Addition of vildagliptin to ongoing insulin therapy may help in terms of overall glycemic control as well as reduction in dose of insulin and weight.
Paresh Ved, Samrat Shah
doaj +2 more sources
Correction: Unravelling the mechanism by which vildagliptin and linagliptin inhibit pyroptosis in lung injury through the NLRP3 inflammatory pathway in type 1 diabetic rats. [PDF]
Sci RepSedik AA +3 more
europepmc +3 more sources
Efficacy and Safety of Vildagliptin Sustained-Release and Metformin Sustained-Release Fixed-Dose Combination in Indian Patients With Type 2 Diabetes Mellitus: A Real-World Perspective. [PDF]
CureusSarda A +9 more
europepmc +3 more sources
Vildagliptin increases butyrate-producing bacteria in the gut of diabetic rats. [PDF]
PLoS ONE, 2017 Emerging evidence supports a key role for the gut microbiota in metabolic diseases, including type 2 diabetes (T2D) and obesity. The dipeptidyl peptidase-4 inhibitor vildagliptin is highly efficacious in treating T2D.
Qian Zhang +7 more
doaj +1 more source
Nanofibrous insulin/vildagliptin core-shell PLGA scaffold promotes diabetic wound healing
Frontiers in Bioengineering and Biotechnology, 2023 Introduction: Slow wound repair in diabetes is a serious adverse event that often results in loss of a limb or disability. An advanced and encouraging vehicle is wanted to enhance clinically applicable diabetic wound care.
Chen-Hung Lee +9 more
doaj +1 more source
Comparison of Vildagliptin and Pioglitazone in Korean Patients with Type 2 Diabetes Inadequately Controlled with Metformin [PDF]
Diabetes & Metabolism Journal, 2016 BackgroundWe compared the efficacies of vildagliptin (50 mg twice daily) relative to pioglitazone (15 mg once daily) as an add-on treatment to metformin for reducing glycosylated hemoglobin (HbA1c) levels in Korean patients with type 2 diabetes ...
Jong Ho Kim +16 more
doaj +1 more source
Clinics and Practice, 2023 (1) Background: There is a high burden of poor glycemic control in the Indian population with type 2 diabetes mellitus (T2DM). Currently, the use of metformin sustained-release (SR)–vildagliptin fixed-dose combination (FDC) is very low as compared to ...
Manoj Chawla +4 more
doaj +1 more source
Efficacy and Safety of Once-Weekly Trelagliptin As Compared to Twice-Daily Vildagliptin in Indian Patients With Type 2 Diabetes Mellitus: A Randomized, Phase 3, Non-inferiority Clinical Trial. [PDF]
CureusDewan B, Shinde S, Roy S.
europepmc +3 more sources