Under physiological conditions, NAC activates the PI3K‐AKT‐COL6A1 axis to sustain redox balance and enhance osteogenesis. COL6A1 deficiency, however, compromises this axis, inducing oxidative stress and impairing NAC's osteogenic efficacy. ABSTRACT Alveolar bone injury represents a prevalent clinical challenge in dentistry, for which stem cell‐based ...
Zhaosong Meng +11 more
wiley +1 more source
Exploration of the mechanism of hesperidin inhibition on the proliferation and metastasis of human breast cancer cells. [PDF]
Liu Z, Chen R.
europepmc +1 more source
A 19‐year‐old woman with intermittent headache and dizziness and a large temporal lobe mass
Brain Pathology, EarlyView.
Sha‐Sha Hu, Wei Yan, Bo Wang
wiley +1 more source
Novel curcumin‐derived M4 binds HSP70's ATPase domain, disrupting HSP70‐mediated lysosomes‐autophagy pathway to inhibit TNBC growth and metastasis, and synergizes with paclitaxel for potent combination therapy. ABSTRACT Structural modification of curcumin yielded a novel series of 1,4‐pentadien‐3‐one oxime ether derivatives, among which compound M4 ...
Zijian Li +6 more
wiley +1 more source
The contribution of ferroptosis to the epithelial-mesenchymal transition phenotype in models of age-related macular degeneration. [PDF]
Yang X +6 more
europepmc +1 more source
When Small Cells Matter: Diagnosing Bladder Small Cell Carcinoma on Urine Cytology
Small cell carcinoma of the bladder is rare, aggressive and diagnostically challenging on urine cytology. We report a case detected in urine and confirmed by cell block immunohistochemistry, highlighting the importance of careful assessment and limitations of the Paris System.
Haley Corbin +3 more
wiley +1 more source
Detection of circulating tumor cells in cholangiocarcinoma via epithelial-mesenchymal transition markers and their application. [PDF]
Liu Y +6 more
europepmc +1 more source
A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou +4 more
wiley +1 more source
Retraction: HMGB2 upregulation promotes the progression of hepatocellular carcinoma cells through the activation of ZEB1/vimentin axis. [PDF]
Editorial Office.
europepmc +1 more source

