Results 71 to 80 of about 236,905 (245)

Unsaturated Phosphorus Electrophiles to Probe Protein Tyrosine Phosphatases

Angewandte Chemie International Edition, Volume 65, Issue 11, 9 March 2026.
Charged aryl‐ethynyl phosphonamidic and phosphonic acids are introduced as low‐reactivity electrophiles for peptide‐based activity probes that enable selective, target‐specific profiling of protein tyrosine phosphatases. The probes show no off‐target cysteine reactivity and engage only the interacting phosphatase in global proteomic analysis.
Eleftheria Poulou, Max Ruwolt, Christian E. Stieger, Kristin Kemnitz‐Hassanin, Christian P. R. Hackenberger   +4 more
wiley   +1 more source

One‐Pot Transition‐Metal‐Free Methods for the Synthesis of All Three Bonds of the Alkyne's Triple Bond

Chemistry – A European Journal, Volume 32, Issue 10, 9 March 2026.
One‐pot transition‐metal‐free methods for the synthesis of all three bonds of the alkyne's triple bond are reviewed. After analysis of several named reactions and discussion of improvements, recent advances in the synthesis of alkynes are discussed. Each section contains a proposed reaction mechanism and analysis of the strengths and weaknesses of the ...
Eugene Kim, Yu Wu, Judith N. Currano, Jianyou Mao, Patrick J. Walsh   +4 more
wiley   +1 more source

Light‐Induced Reactions of Small‐Membered Cyclic Carbonyl Compounds

European Journal of Organic Chemistry, Volume 29, Issue 10, 9 March 2026.
This review highlights recent advances in the synthesis and photochemical reactivity of cyclopropenone and cyclobutenedione. These compounds undergo photolysis upon direct excitation, and in some cases, through indirect excitation by photocatalysts. The resulting photogenerated species exhibit unique reactivity profiles that are strongly influenced by ...
Kenji Mishiro
wiley   +1 more source

Organophotocatalytic synthesis of phosphoramidates

, 2016
We describe the use of visible light in conjunction with an organic dye for the synthesis of phosphoramidates. Cross dehydrogenative coupling reactions between phosphites and amines are reported using organic dyes and light as catalysts for the first ...
Hao, Guo, Kowalczuk, Agnieszka, Meazza, Marta, Rios, Ramon, Shirley, Luke, Yang, Jung Woon   +5 more
core   +1 more source

1,3-Dien-5-ynes: Versatile Building Blocks for the Synthesis of Carbo- and Heterocycles [PDF]

, 2016
1,3-Dien-5-ynes have been extensively used as starting materials for the synthesis of a wide number of different carbo- and heterocycles. The aim of this review is to give an overview of their utility in organic synthesis, highlighting the variety of ...
Aguilar, Enrique, Fernández Rodríguez, Manuel A., García García, Patricia, Sanz Díez, Roberto   +3 more
core   +1 more source

Silent Partners in the Mill: Unveiling the Role of Additives in Mechanochemical Synthesis

Chemistry – A European Journal, Volume 32, Issue 9, 2 March 2026.
Mechanochemistry offers a sustainable, solvent‐free alternative to traditional synthesis, often enhanced by additives in a process known as additive‐assisted grinding. This review discusses how various additives, including liquids, ionic solids, and advanced materials like ionic liquids and piezoelectric compounds, improve reaction efficiency ...
Johanna Breinsperger, Nika Podlesnik, Francesco Mele, Michael Schnürch   +3 more
wiley   +1 more source

Studies on the biodistribution of dextrin nanoparticles [PDF]

, 2010
The characterization of biodistribution is a central requirement in the development of biomedical applications based on the use of nanoparticles, in particular for controlled drug delivery.
Ferreira, M. F. M., Gama, F. M., Geraldes, C. F. G. C., Gonçalves, C., Martins, J. A., Prata, M. I. M., Santos, A. C.   +6 more
core   +1 more source

Highly Tunable and Cell‐Remodelable Thiol‐ene Alginate‐Peptide Crosslinked Hydrogels to Recreate Cellular and Organoid Microenvironments for Biofabrication

Advanced Healthcare Materials, Volume 15, Issue 9, 6 March 2026.
Norbornene‐functionalized alginate is crosslinked with a di‐thiolated peptide sequence cleavable by cell‐secreted matrix metalloproteinases and decorated with cell‐adhesion peptides upon exposure to UV. Thyroid follicles, endometrial and intestinal organoids are encapsulated in a gentle manner with high cell viability and correct phenotype ...
Julia Fernández‐Pérez, Adrián Seijas‐Gamardo, Antonio J. Feliciano, Panagiota Kakni, Anna M. Kip, Paul Wieringa, Stefan Giselbrecht, Matthew B. Baker, Lorenzo Moroni   +8 more
wiley   +1 more source

Dirhodium-catalyzed C-H arene amination using hydroxylamines [PDF]

, 2016
Primary and N-alkyl arylamine motifs are key functional groups in pharmaceuticals, agrochemicals, and functional materials, as well as in bioactive natural products. However, there is a dearth of generally applicable methods for the direct replacement of
Adebesin, Adeniyi Michael, Burt, Scott R., Ess, Daniel H., Falck, John R., Kürti, László, Ma, Zhiwei, Paudyal, Mahesh P.   +6 more
core   +1 more source

Indeed, No Need for HMPA! A DFT Study Comparing the Lewis Basicity of Phosphoric Acid Triamides

ChemistryEurope, Volume 4, Issue 3, March 2026.
High‐level density functional theory calculations of the interactions of protons, lithium cations, and samarium(II) and samarium(III) species with a series of Lewis bases reveal that TPPA and HAPO‐2 are stronger donor compounds than HMPA. Therefore, they should by excellent substitutes of carcinogenic and mutagenic HMPA in many reactions.
Luca Steiner, Frederic Schubert, Beate Paulus, Hans‐Ulrich Reissig   +3 more
wiley   +1 more source