Results 101 to 110 of about 2,052,059 (368)

Violence and Complexity [PDF]

open access: yesThe Open Psychology Journal, 2015
Like all the phenomena that the human mind is knowledgeable about, the phenomenon of violence should be regarded as a complex macrosystem, where systems of networks and agents are linked and interact at different interconnected levels. This means that complexity refers to the phenomenon per se, to the various cognitive and emotional processes through ...
openaire   +6 more sources

The Aftermath of Terrorism: Posttraumatic Stress and Functional Impairment after the 2011 Oslo bombing

open access: yesFrontiers in Psychology, 2015
Objective. In the present study we wanted to investigate the link between exposure, posttraumatic stress symptomatology and functional impairment in the aftermath of terrorism.Method.
Øivind eSolberg   +2 more
doaj   +1 more source

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

open access: yesMolecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita   +1 more
wiley   +1 more source

Q fever outbreak in the terraced vineyards of Lavaux, Switzerland

open access: yesNew Microbes and New Infections, EarlyView., 2014
Abstract Coxiella burnetii infection (Q fever) is a widespread zoonosis with low endemicity in Switzerland, therefore no mandatory public report was required. A cluster of initially ten human cases of acute Q fever infections characterized by prolonged fever, asthenia and mild hepatitis occurred in 2012 in the terraced vineyard of Lavaux ...
C. Bellini   +9 more
wiley   +1 more source

Intimate Partner Violence and Sexual Violence in Bristol Bay: Key Results from the 2011 Alaska Victimization Survey [PDF]

open access: yes, 2011
This document is a two-page summary of the key results from the 2011 Alaska Victimization Survey for the Brisol Bay region, which was conducted from April to June 2011, with results released on October 12, 2011 in Dillingham. Findings include: * Over
Rosay, André B.
core  

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

open access: yesMolecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi   +5 more
wiley   +1 more source

Ecological pathways to prevention: How does the SASA! community mobilisation model work to prevent physical intimate partner violence against women?

open access: yesBMC Public Health, 2016
Background Intimate partner violence (IPV) against women is a global public health concern. While community-level gender norms and attitudes to IPV are recognised drivers of IPV risk, there is little evidence on how interventions might tackle these ...
Tanya Abramsky   +7 more
doaj   +1 more source

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas   +15 more
wiley   +1 more source

Multiplex single‐cell profiling of putative cancer stem cell markers ALDH1, SOX9, SOX2, CD44, CD133 and CD15 in endometrial cancer

open access: yesMolecular Oncology, EarlyView.
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien   +7 more
wiley   +1 more source

Intimate Partner Violence and Sexual Violence in the City and Borough of Sitka: Key Results from the 2012 Alaska Victimization Survey [PDF]

open access: yes, 2012
This document is a two-page summary of the key results from the 2012 Alaska Victimization Survey for the City and Borough of Sitka, which was conducted from March to May 2012, with results released on October 19, 2012 in Sitka. Findings include: * 47%
Rosay, André B.
core  

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