Results 161 to 170 of about 2,799,905 (389)

Outcomes of image-based sexual abuse among young people: a systematic review

open access: yesFrontiers in Psychology
Image-Based Sexual Abuse (IBSA) is an increasingly recognized issue, especially among young people, yet empirical research on its consequences remains relatively scarce.
Per Moum Hellevik   +3 more
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

SEX BEFORE VIOLENCE: GIRLS, DATING VIOLENCE, AND (PERCEIVED) SEXUAL AUTONOMY [PDF]

open access: yes, 2006
This article explores the phenomenon of girl violence by examining teen dating violence and girls\u27 experiences with intimate abuse both as victims and as perpetrators. While there is a tendency to view women\u27s experiences as victims of violence as
Hanna, Cheryl
core   +1 more source

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

open access: yesMolecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li   +12 more
wiley   +1 more source

Purchaser, firearm, and retailer characteristics associated with crime gun recovery: a longitudinal analysis of firearms sold in California from 1996 to 2021

open access: yesInjury Epidemiology
Background Firearm violence is a major cause of death and injury in the United States. Tracking the movement of firearms from legal purchase to use in crimes can help inform prevention of firearm injuries and deaths. The last state-wide studies analyzing
Sonia L. Robinson   +4 more
doaj   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

open access: yesMolecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi   +12 more
wiley   +1 more source

Domestic Violence: The Criminal Law Response. [PDF]

open access: yes, 2013
Domestic violence is serious and should be severely dealt with by the criminal law. There is no offence of domestic violence as such; instead the criminal law responds to it with a number of different offences which are examined in this article, as is ...
Parsons, Simon
core  

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