Results 21 to 30 of about 235,748 (267)

Efficacy and Tolerability of Topotecan/Cyclophosphamide/Dinutuximab in Relapsed and Refractory High‐Risk Neuroblastoma: A Multi‐Institutional Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Chemoimmunotherapy with irinotecan, temozolomide, and dinutuximab (I/T/DIN) has emerged as first‐line therapy for relapsed/refractory (r/r) high‐risk neuroblastoma (HRNB) in North America. Topotecan and cyclophosphamide (T/C) are often used in combination with dinutuximab in the setting of lack of response, progression, or incomplete ...
Benjamin J. Lerman, Madeleine King, Rajen Mody, Sara‐Jane Onyeama, Araz Marachelian, Thomas Cash, Sara M. Federico, Meaghan Granger, Ami V. Desai, Suzanne Shusterman, Jennifer H. Foster, Elizabeth Sokol, Chelsee Greer, Keri Streby, Holly J. Meany, Kieuhoa T. Vo, Margaret E. Macy, Rochelle Bagatell   +17 more
wiley   +1 more source

Single-year change in views of democracy and society and support for political violence in the USA: findings from a 2023 nationally representative survey

Injury Epidemiology
Background A 2022 survey in the USA found concerningly high prevalences of support for and personal willingness to engage in political violence, of beliefs associated with such violence, and of belief that civil war was likely in the near future.
Garen J. Wintemute, Sonia L. Robinson, Andrew Crawford, Elizabeth A. Tomsich, Paul M. Reeping, Aaron B. Shev, Bradley Velasquez, Daniel Tancredi   +7 more
doaj   +1 more source

Violence against children, later victimisation, and mental health: a cross-sectional study of the general Norwegian population [PDF]

European Journal of Psychotraumatology, 2015
Background: Violence in childhood is associated with mental health problems and risk of revictimisation. Less is known about the relative importance of the various types of childhood and adult victimisation for adult mental health. Objective: To estimate
Siri Thoresen, Mia Myhre, Tore Wentzel-Larsen, Helene Flood Aakvaag, Ole Kristian Hjemdal   +4 more
doaj   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Early outreach to survivors of the shootings in Norway on the 22nd of July 2011 [PDF]

European Journal of Psychotraumatology, 2014
Background: Under-treatment and unmet needs among survivors have been documented years after terror attacks. Improved early and proactive outreach strategies, including targeted interventions for individuals in need, are required.
Grete Dyb, Tine Jensen, Kristin Alve Glad, Egil Nygaard, Siri Thoresen   +4 more
doaj   +1 more source

Changes in Violence and Clinical Distress Among Men in Individual Psychotherapy for Violence Against Their Female Partner: An Explorative Study

Frontiers in Psychology, 2021
Most interventions for men who have acted violently toward their partner have been conducted as group interventions within a criminal justice context.
Ingunn Rangul Askeland, Ingunn Rangul Askeland, Marianne Skogbrott Birkeland, Bente Lømo, Bente Lømo, Odd Arne Tjersland   +5 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Changes in the prevalence of forcible rape, physical violence, and physical partner violence among men and women in Norway: a population-based repeated cross-sectional study in 2013 and 2022

BMC Public Health
Background Repeated prevalence studies are necessary to monitor the government's progress toward preventing community violence over time. This study aims to identify possible changes in self-reported physical violence, forcible rape, and physical partner
Maria T. Grønning Dale, Helene Flood Aakvaag, Alexander Nissen, Ida Frugård Strøm   +3 more
doaj   +1 more source

Testing the leadership and organizational change for implementation (LOCI) intervention in Norwegian mental health clinics: a stepped-wedge cluster randomized design study protocol

Implementation Science, 2019
Background Alignment across levels of leadership within an organization is needed for successful implementation of evidence-based practice. The leadership and organizational change for implementation (LOCI) intervention is a multi-faceted multilevel ...
Karina M. Egeland, Ane-Marthe Solheim Skar, Mathilde Endsjø, Erlend Høen Laukvik, Harald Bækkelund, Aida Babaii, Lene Beate Granly, Gry Kristina Husebø, Randi Hovden Borge, Mark G. Ehrhart, Marisa Sklar, C. Hendricks Brown, Gregory A. Aarons   +12 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source