Results 21 to 30 of about 1,752,971 (193)
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
Long-Term Physical and Mental Health Effects of Domestic Violence [PDF]
, 2014 Domestic violence is an issue affecting people of all ages, races, genders, and sexual orientations. Violence against men and same-sex domestic violence are often considered less of a threat to society and to the people involved, but it is important to ...
Alejo, Kavita
core +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Cure Violence: A Public Health Model to Reduce Gun Violence [PDF]
, 2015 Scholars and practitioners alike in recent years have suggested that real and lasting progress in the fight against gun violence requires changing the social norms and attitudes that perpetuate violence and the use of guns.
Caterina Gouvis Roman +3 more
core +1 more source
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
FEBS Letters, EarlyView.Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze +3 more
wiley +1 more source
Intimate Partner Violence and Sexual Violence in the State of Alaska: Key Results from the 2015 Alaska Victimization Survey [PDF]
, 2016 Council on Domestic Violence and Sexual Assault, Alaska Department of Public SafetyThis document is a two-page summary of the key results from the 2015 Alaska Victimization Survey (AVS) for Alaska statewide and trends from 2010 to 2015, which show a ...
Morton, Lauree, Rosay, André B.
core
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
Intimate Partner Violence and Sexual Violence in the Kodiak Island Borough: Key Results from the 2012 Alaska Victimization Survey [PDF]
, 2012 This document is a two-page summary of the key results from the 2012 Alaska Victimization Survey for the Kodiak Island Borough, which was conducted from March to May 2012, with results released on October 4, 2012 in Kodiak.
Rosay, André B.
core
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source
Intimate Partner Violence and Sexual Violence in Bristol Bay: Key Results from the 2011 Alaska Victimization Survey [PDF]
, 2011 This document is a two-page summary of the key results from the 2011 Alaska Victimization Survey for the Brisol Bay region, which was conducted from April to June 2011, with results released on October 12, 2011 in Dillingham. Findings include: * Over
Rosay, André B.
core