Results 31 to 40 of about 1,001,579 (299)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Changes in the prevalence of forcible rape, physical violence, and physical partner violence among men and women in Norway: a population-based repeated cross-sectional study in 2013 and 2022

BMC Public Health
Background Repeated prevalence studies are necessary to monitor the government's progress toward preventing community violence over time. This study aims to identify possible changes in self-reported physical violence, forcible rape, and physical partner
Maria T. Grønning Dale, Helene Flood Aakvaag, Alexander Nissen, Ida Frugård Strøm   +3 more
doaj   +1 more source

Good soldiers in implementation: validation of the Implementation Citizenship Behavior Scale and its relation to implementation leadership and intentions to use evidence-based practices

Implementation Science Communications, 2021
Background Implementation citizenship behavior (ICB) describes extra-role behaviors performed by employees to support evidence-based practice (EBP) implementation. Such behaviors can be measured using the Implementation Citizenship Behavior Scale (ICBS),
Randi Hovden Borge, Ane-Marthe Solheim Skar, Mathilde Endsjø, Karina M. Egeland   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Police Views of Suicidal Persons and the Law Criminalizing Attempted Suicide in Ghana: A Qualitative Study With Policy Implications

SAGE Open, 2017
The penal code of Ghana condemns suicide attempt. The present study sought to explore the views of the police on persons who attempt suicide and the law criminalizing the act.
Joseph Osafo, Charity S. Akotia, Emmanuel N.-B. Quarshie, Kofi E. Boakye, Johnny Andoh-Arthur   +4 more
doaj   +1 more source

The relationship between posttraumatic stress symptoms and narrative structure among adolescent terrorist-attack survivors

European Journal of Psychotraumatology, 2016
Background: The structure of trauma narratives is considered to be related to posttraumatic stress symptomatology and thus the capacity to make a coherent narrative after stressful events is crucial for mental health.
Petra Filkuková, Tine K. Jensen, Gertrud Sofie Hafstad, Hanne Torvund Minde, Grete Dyb   +4 more
doaj   +1 more source

Violence against children, later victimisation, and mental health: a cross-sectional study of the general Norwegian population [PDF]

European Journal of Psychotraumatology, 2015
Background: Violence in childhood is associated with mental health problems and risk of revictimisation. Less is known about the relative importance of the various types of childhood and adult victimisation for adult mental health. Objective: To estimate
Siri Thoresen, Mia Myhre, Tore Wentzel-Larsen, Helene Flood Aakvaag, Ole Kristian Hjemdal   +4 more
doaj   +1 more source

Changes in Violence and Clinical Distress Among Men in Individual Psychotherapy for Violence Against Their Female Partner: An Explorative Study

Frontiers in Psychology, 2021
Most interventions for men who have acted violently toward their partner have been conducted as group interventions within a criminal justice context.
Ingunn Rangul Askeland, Ingunn Rangul Askeland, Marianne Skogbrott Birkeland, Bente Lømo, Bente Lømo, Odd Arne Tjersland   +5 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Testing the leadership and organizational change for implementation (LOCI) intervention in Norwegian mental health clinics: a stepped-wedge cluster randomized design study protocol

Implementation Science, 2019
Background Alignment across levels of leadership within an organization is needed for successful implementation of evidence-based practice. The leadership and organizational change for implementation (LOCI) intervention is a multi-faceted multilevel ...
Karina M. Egeland, Ane-Marthe Solheim Skar, Mathilde Endsjø, Erlend Høen Laukvik, Harald Bækkelund, Aida Babaii, Lene Beate Granly, Gry Kristina Husebø, Randi Hovden Borge, Mark G. Ehrhart, Marisa Sklar, C. Hendricks Brown, Gregory A. Aarons   +12 more
doaj   +1 more source