Results 51 to 60 of about 1,028,469 (308)

Prison violence and the mission statement [PDF]

, 1994
A report prepared by the Prison Violence Project, Kingston, Ontario, April 16, 1994. Rudolf Martens, Chairperson; J. Campbell, Research Director. Discusses the achievements and failures of the prison system after the adoption of a "mission statement" in ...
Prison Violence Project
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Changes in firearm intentions and behaviors after the 2024 United States presidential election

Injury Epidemiology
Background Firearm purchasing patterns, intentions, and behaviors change over time in response to specific events. Additionally, the nature of these changes may be evolving over time or differ depending on the nature of the event in question.
Michael D. Anestis, Allison E. Bond, Kimberly C. Burke, Sultan Altikriti, Daniel C. Semenza   +4 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Understanding agency and resistance strategies (UNARS): children’s experiences of domestic violence [PDF]

, 2015
This report focuses on children’s experiences of domestic violence, in families affected by domestic violence. Our report is concerned with children’s experiences in situations where the main perpetrator and victim of violence would be legally defined as
Callaghan, Jane E M, Alexander, Joanne H, Callaghan, Jane, Alexander, Jo   +3 more
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

The mediating role of shame in the relationship between childhood bullying victimization and adult psychosocial adjustment

European Journal of Psychotraumatology, 2018
Background: Psychological distress following experiencing bullying victimization in childhood has been well documented. Less is known about the impact of bullying victimization on psychosocial adjustment problems in young adulthood and about potential ...
Ida Frugård Strøm, Helene Flood Aakvaag, Marianne Skogbrott Birkeland, Erika Felix, Siri Thoresen   +4 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Association of medical conditions and firearm suicide among legal handgun purchasers in California: a case–control study

Injury Epidemiology, 2023
Background Suicide is a pressing public health problem, and firearm owners are at especially elevated risk. Certain health conditions are markers of suicide risk, but more research is needed on clinical risk markers for suicide among firearm owners ...
Julia P. Schleimer, Rose M. C. Kagawa, Hannah S. Laqueur   +2 more
doaj   +1 more source

Kaupapa Māori wellbeing framework: the basis for whānau violence prevention and intervention [PDF]

, 2014
With Māori over-represented in family violence statistics as both victims and perpetrators, this paper identifies some key considerations for implementing violence prevention and intervention initiatives.
Terry Dobbs, Moana Eruera
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