Communities Engaged in Resisting Violence [PDF]
"Communities Engaged in Resisting Violence" documents a new movement in Chicago that seeks to end violence against women through community engagement and accountability, rather than solely social services and criminal justice.
Ann Russo, Melissa Spatz
core
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Intimate Partner Violence and Sexual Violence in Bristol Bay: Key Results from the 2011 Alaska Victimization Survey [PDF]
This document is a two-page summary of the key results from the 2011 Alaska Victimization Survey for the Brisol Bay region, which was conducted from April to June 2011, with results released on October 12, 2011 in Dillingham. Findings include: * Over
Rosay, André B.
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An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Long-Term Physical and Mental Health Effects of Domestic Violence [PDF]
Domestic violence is an issue affecting people of all ages, races, genders, and sexual orientations. Violence against men and same-sex domestic violence are often considered less of a threat to society and to the people involved, but it is important to ...
Alejo, Kavita
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Intimate Partner Violence and Sexual Violence in the City and Borough of Sitka: Key Results from the 2012 Alaska Victimization Survey [PDF]
This document is a two-page summary of the key results from the 2012 Alaska Victimization Survey for the City and Borough of Sitka, which was conducted from March to May 2012, with results released on October 19, 2012 in Sitka. Findings include: * 47%
Rosay, André B.
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AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Interpersonal violence in peacetime Malawi. [PDF]
Background: The contribution of interpersonal violence (IPV) to trauma burden varies greatly by region. The high rates of IPV in sub-Saharan Africa are thought to relate in part to the high rates of collective violence.
Charles, Anthony G. +7 more
core +3 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source

