Results 81 to 90 of about 903,159 (295)

PD‐L1‐Binding Antigen Presenters: Redirecting Vaccine‐Induced Antibodies for Cancer Immunotherapy

Advanced Science, EarlyView.
The PBAP‐gE complex anchors gE antigen to PD‐L1 on tumor cells. Vaccine‐induced anti‐gE antibodies simultaneously engage FcγRIIIa on NK cells and tumor‐bound PBAP‐gE, triggering NK cell activation and antibody‐dependent cellular cytotoxicity, thereby selectively eliminating PD‐L1–expressing tumor cells.
Huixin Gao, Lijuan Lu, Xiaoxiao Xiong, Yi Li, Donghui Hu, Duo Zhang, Zhiwei Feng, Cong Liu, Nannan Liu, Xiaoli Li, Jizhou Tan, Ting Liu, Ling Peng, Lu Lu, Huiyi Feng, Yan Zhong, Guisen Tan, Zhicheng Zhang, Liqin Huang, Chao Su, Ying Xue, Shuo Song, Wenxia Fan, Wei Wang, Fan Zou   +24 more
wiley   +1 more source

Kajian Kriminologi Terhadap Upaya Penanganan Kasus Kekerasan Dalam Rumah Tangga (KDRT) Di Indonesia

Veritas et Justitia, 2016
Domestic violence had been and is still underreported.  Inhibiting factor is the widely held perception that outside intervention in cases of domestic violence is unwelcome and asking outside help will bring shame to the family.
Prisilla Viviane Merung
doaj   +1 more source

Honour-related violence (HRV) in Scotland: A cross- and multi-agency intervention involvement survey [PDF]

, 2007
This paper documents the results of a small-scale pilot study, which represents the first step towards further research in this overlooked area of violence against women and represents a first step towards responding to widespread calls for multi ...
Khan, R
core  

Crossing boundaries: women's gossip, insults and violence in sixteenth-century France [PDF]

, 2011
Using evidence from cases recorded in the registers of the consistories of southern France, the author investigates the way in which Languedocian women policed each other's behaviour, enforcing a collective morality through gossip, sexual insult and ...
Lipscomb, Suzannah
core   +1 more source

miR‐135a‐5p Is a Promising Target to Prevent the Glomerulosclerosis Associated with Podocyte Developmental Toxicity in Offspring Induced by Prenatal Dexamethasone Exposure

Advanced Science, EarlyView.
Prenatal dexamethasone exposure (PDE) programs persistent podocyte developmental injury and adult glomerulosclerosis. Mechanistically, glucocorticoid receptor (GR) binds the miR‐135a‐5p promoter and recruits the histone acetyltransferase p300, increasing promoter histone acetylation and sustaining miR‐135a‐5p expression. Elevated miR‐135a‐5p suppresses
Xiaoqi Zhao, Haiyun Chen, Yanan Zhu, Zhiping Xia, Hangyuan He, Yutang Liu, Tianshu Yang, Hui Wang, Ying Ao   +8 more
wiley   +1 more source

Co‐Design Workshops to Develop a Psychosocial Support Service Model for Refugees in Sweden Affected by Gender‐Based Violence

Health Expectations
Background Experiencing gender‐based violence (GBV) is common among refugees. Intersecting systems of oppression can increase the risk of GBV and of suffering detrimental consequences, while concurrently creating barriers to meaningful support.
Anna Pérez‐Aronsson, Elin Inge, Heba Alanbari, Iman Alsalamah, Miras Ghannoum, Zozan Abu Mohammad, Frida Johansson Metso, Frida Holmqvist, Johanna Belachew, Tove Filén, Frida Pålsson Hennoks, Anna Sarkadi, Georgina Warner   +12 more
doaj   +1 more source

Health and the primary prevention of violence against women [PDF]

This position paper focuses on the primary prevention of violence perpetrated by men against women. It develops a position on primary prevention (as distinct from secondary and tertiary interventions).

core  

Commentary: Actions to end violence against women : a multi-sector approach [PDF]

, 2015
Many forms of violence affect women and girls, such as physical and sexual abuse, trafficking, female genital mutilation, early and forced marriage, murders in the name of honour or dowry, and sexual harassment and abuse by authority figures.
García-Moreno, Claudia, Temmerman, Marleen   +1 more
core   +4 more sources

SMAD4 Palmitoylation Drives a Metabolic‐Transcriptional Circuit to Promote Tumorigenesis and Confers Radiosensitivity in Pancreatic Cancer

Advanced Science, EarlyView.
This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang, Shan Zhang, Junping Bai, Xiaobing Li, Yi Han, Min Ji, Chongyi Jiang, Xiaobei Ge, Tianyu Yu, Yongying Hou, Jun Zhang, Wangting Li, Yiran Song, Jiaying Cai, Yingqun Zhou, Liwei An, Feng Wang   +16 more
wiley   +1 more source

VICTIMS OF SEXUAL VIOLENCE ATTENDED IN A SPECIALIZED SERVICE

Cogitare Enfermagem, 2015
The aim was to investigate aspects of sexual violence and the victims’ adherence to outpatient follow-up. This transversal study involved retrospective data collection in a specialized service in the Brazilian state of Paraná.
Tatiane Herreira Trigueiro, Miriam Aparecida Barbosa Merighi, Adeli Regina Prizybicien de Medeiros, Cléa Elisa Lopes Ribeiro, Nely Dayse Santos da Mata, Maria Cristina Pinto de Jesus   +5 more
doaj   +1 more source