Results 91 to 100 of about 92,388 (260)
Biotechnology Progress, EarlyView.Abstract Traditional off‐line analysis methods to quantify residual metabolite concentrations in a drug substance fermentation process consume valuable time, require costly resources, and demand potentially hazardous manual operations when working with pathogenic biological organisms.
Griffin P. Thomas +7 more
wiley +1 more source
Chronic Diseases and Translational Medicine, EarlyView.Shared differential metabolites identified across the three sample groups. (A) Venn diagram of differential metabolites between the two comparison groups; Based on the detected levels of these overlapping differential metabolites, (B) d‐Arabitol, (C) Triclosan, (D) Iloprost, (E) Tetracosanoic acid, and (F) Omeprazole sulfone. Box plots were constructed
Mengtao Qian +4 more
wiley +1 more source
AMA Journal of Ethics, 2001 Little-known trivia about famous patients. Virtual Mentor is a monthly bioethics journal published by the American Medical Association.
openaire +2 more sources
Chemistry – A European Journal, EarlyView.Biotinylation of a fluorescein‐based photosensitizer enhances its performance in PDT through a synergistic dual action. In addition to Type II singlet oxygen generation common to both dyes, the biotinylated system induces stronger membrane perturbation and higher local accumulation in lipid membranes, associated with increased water permeability and ...
Valeria Butera +4 more
wiley +1 more source
Population Genomics Insights into Pharmacogenomic Differentiation Between East Asians and Europeans
Clinical Pharmacology &Therapeutics, EarlyView.Genetic variation contributes substantially to interindividual and interpopulation differences in drug response, yet most pharmacogenomic studies remain biased toward European populations. Here, we systematically assessed pharmacogenomic variation across East Asians (EAS) and Europeans (EUR) using public genomic datasets and investigated the potential ...
Sihan Chen, Hongpu Chen, Shuhua Xu
wiley +1 more source
Heterogeneity of VIP receptors.
Archives internationales de pharmacodynamie et de therapie, 1990 info:eu-repo/semantics ...
Robberecht, Patrick +3 more
openaire +2 more sources
Clinical Pharmacology &Therapeutics, EarlyView.Genetic polymorphisms are common in pharmacogenes, with sometimes important implications for drug metabolism. Assessing the correct enzyme phenotype from genetic data is thus a crucial step into the development of personalized medicine. Many bioinformatics star‐allele callers have been developed for this purpose of identifying the correct star alleles ...
Marc B. Gros‐La‐Faige +2 more
wiley +1 more source
Drug Testing and Analysis, EarlyView.A fatal 3‐chloro‐phencyclidine (3‐Cl‐PCP) intoxication was investigated by analyzing postmortem samples and a pooled human liver microsomes assay. Tentative metabolite identification was performed by liquid chromatography‐quadrupole time‐of‐flight mass spectrometry (LC‐QTOF‐MS). Seven phase I metabolites were identified.
Johannes Kutzler +3 more
wiley +1 more source
Dynamic response at the terminus of oblique intersecting joints subjected to stress waves
Deep Underground Science and Engineering, EarlyView.This study derives the propagation equation for stress waves impinging upon nonlinear oblique intersecting joints. It analyzes the dynamic response at the terminus of nonlinear oblique intersecting joints subjected to stress waves. Abstract To investigate the dynamic response at the terminus of oblique intersecting joints subjected to stress waves, a ...
Gang Hu +4 more
wiley +1 more source
Epilepsia, EarlyView.Abstract Objective Pathogenic variants in the calcium/calmodulin‐dependent protein kinase II B gene (CAMK2B) have been associated with neurodevelopmental disorders, including epilepsy, yet the mechanisms underlying cortical dysfunction remain largely unclear.
Hiroki Mutoh +3 more
wiley +1 more source