Results 61 to 70 of about 92,807 (260)
口腔疾病防治, 2016 Objective To evaluate the apical sealing ability of different obturationtechniques in oval-root canals.Methods After root canals shaping with Mtwo instruments, 42 premolars with oval-root canals were randomly divided into 3 groups of 14 teeth each. Group
YANG Qin +4 more
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Advanced Science, EarlyView.Orally administered, pH‐responsive Co‐SAN exerts dual functions: in the alkaline intestinal milieu, it scavenges reactive oxygen species (ROS) and suppresses the PI3K/AKT pathway and NETs formation, thus providing radioprotection; whereas in the acidic tumor microenvironment, it generates ROS and alleviates hypoxia, thereby enhancing radiosensitization.
Shengqi Yin +13 more
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AnimalsFeline pyothorax or thoracic empyema is a condition characterized by the accumulation of purulent exudate within the thoracic cavity due to infection [...]
Hyomi Jang +8 more
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Advanced Science, EarlyView.In the pathological context of osteoarthritis (OA), the phosphorylation of AKT1 at Ser473 enhances its binding to Lys140 of Insig1, which facilitates the formation of AKT1–Insig1 complex. Subsequently, the activation of AKT1 promotes the phosphorylation of Insig1 at Ser189, potentially enhancing the dissociation of Insig1 from sterol regulatory element‑
Xiaoqi Zhang +19 more
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Advanced Science, EarlyView.Schematic diagram showing compressive stress triggers glycolytic reprogramming and lactate accumulation in macrophages. Lactate mediates TRAF6 lactylation at K171/K180 dual sites, which enhances its K63‐linked ubiquitination to activate the NF‑κB pathway and promote M1 polarization. This cascade drives orthodontic tooth movement (OTM) and alveolar bone
Xinyi He +9 more
wiley +1 more source
Zhongguo cuzhong zazhi目的 探讨空腹血糖与接受静脉溶栓的缺血性卒中患者功能结局的关系。 方法 回顾性收集2018年10月—2020年11月首都医科大学附属北京天坛医院静脉溶栓患者的病历资料。纳入发病4.5 h内接受阿替普酶静脉溶栓的缺血性卒中患者为研究对象，采集相关研究数据（包括空腹血糖等）。研究结局设定为出院时功能结局良好，即mRS评分0～1分。采用多因素logistic回归分析探讨空腹血糖与功能结局的关联性。 结果 共入组205例患者，平均年龄为（63.21±11.67）岁，其中153例（74.63%）患者为男性 ...
丁则昱1，李光硕1，赵性泉1，2 (DING Zeyu1, LI Guangshuo1, ZHAO Xingquan1,2 )
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CALB2 is a Mechanoresistance Gene in Metastatic Prostate Cancer
Advanced Science, EarlyView.Prostate cancer cell lines of differing origins were cultured over many passages while being subjected to semi‐lethal levels of fluid shear stress, representing the harsh mechanical environment these cells are subjected to in the circulation during the process of distant metastasis.
Abigail R. Fabiano +10 more
wiley +1 more source
Zhongguo cuzhong zazhi2024年6月，《中华神经科杂志》发布了更新版的《中国急性缺血性卒中诊治指南2023》。该指南基于最新的循证医学证据，提供了急性缺血性卒中（acute ischemic stroke，AIS）诊治的最新推荐意见，涵盖急性期静脉溶栓、机械取栓、二级预防抗血小板治疗等多个方面。本文深入剖析这些关键推荐，结合AIS领域的最新研究成果，对相关文献进行深入解读。本文旨在清晰呈现AIS的最新诊治规范，为临床医师提供实用的指导，以更好地服务AIS患者，改善其治疗效果。 Abstract: In June ...
李光硕1，赵性泉1，2 (LI Guangshuo1, ZHAO Xingqua1,2 )
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Factors affecting the length of fiber post and core structure: a literature review
口腔疾病防治, 2017 An ideal balance between the post length within root and the coronal extension should exist. Some theo⁃ ries advocated the use of the longest post as possible as the apical seal is not disturbed. Others advocated that the post should be longer than the
LIN Jie +4 more
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Chemoselective Metabolomics via a Modular Reactivity‐Encoding Platform
Advanced Science, EarlyView.Conventional LC–MS underrepresents numerous metabolites due to heterogeneous ionization efficiencies and matrix interference. Here, we introduce a modular reactivity‐encoding platform (MREP) comprising four alkyne‐tagged probes that selectively derivatize key functional groups, followed by unified click‐chemistry capture to eliminate matrix components ...
Xin Tao +10 more
wiley +1 more source