Results 101 to 110 of about 64,120 (294)

Systemic lupus erythematosus‐associated autoantibodies in sickle cell disease: Spontaneous emergence in a patient and in transgenic sickle mice

open access: yesBritish Journal of Haematology, Volume 206, Issue 4, Page 1213-1217, April 2025.
Summary We describe a patient with sickle cell disease (SCD) and elevated antiphospholipid antibodies (aPL) who developed multi‐organ failure resembling catastrophic antiphospholipid syndrome. Autoimmune screening revealed several autoantibodies characteristic of systemic lupus erythematosus (SLE). Notably, routinely housed and unmanipulated transgenic
Urshita Sinha   +8 more
wiley   +1 more source

Thromboelastometry (ROTEM) Assessing Hypercoagulability in Patients Referred for Thrombophilia Screening

open access: yesInternational Journal of Laboratory Hematology, Volume 47, Issue 3, Page 520-528, June 2025.
ABSTRACT Introduction Thrombophilia, a blood coagulation disorder, poses risks of venous thromboembolism (VTE). Coagulation assays may not be sufficient to assess VTE risk and global assays such as Rotational Thromboelastometry (ROTEM) may add valuable information.
Mazen Assar   +5 more
wiley   +1 more source

Activated Protein C Resistance Testing: An Update From Australasia/Asia‐Pacific

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Activated protein C resistance (APCR) represents a risk factor for thrombosis and is usually due to factor V Leiden (FVL). Clinicians may order either test (i.e., APCR or FVL) to help assess ‘thrombophilia’ in patients who present with thrombosis. APCR testing is usually achieved using clot‐based assays, whereas FVL is assessed by
Emmanuel J. Favaloro   +8 more
wiley   +1 more source

First Results from Viper: Detection of Small-Scale Anisotropy at 40 GHZ [PDF]

open access: yes, 1999
Results of a search for small-scale anisotropy in the cosmic microwave background (CMB) are presented. Observations were made at the South Pole using the Viper telescope, with a .26 degree (FWHM) beam and a passband centered at 40 GHz. Anisotropy band-power measurements in bands centered at l = 108, 173, 237, 263, 422 and 589 are reported ...
arxiv   +1 more source

Measuring Direct Oral Anticoagulant (DOAC) Levels: Applications, Limitations, and Future Directions

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction There are important challenges with the measurement and interpretation of direct oral anticoagulant (DOAC) anticoagulant effect including a lack of therapeutic ranges, inaccuracy of routinely available coagulation assays, lack of established thresholds for clinically significant effect, and uncertainty about how to apply the ...
Siraj Mithoowani   +2 more
wiley   +1 more source

Venom proteomic analysis of medically important Nigerian viper Echis ocellatus and Bitis arietans snake species

open access: yesBiochemistry and Biophysics Reports, 2021
Snakebite envenoming remains a neglected tropical disease which poses severe health hazard, especially for the rural inhabitants in Africa. In Nigeria, vipers are responsible for the highest number of deaths. Hydrophilic interaction liquid chromatography
Emeka John Dingwoke   +6 more
doaj  

Impact of Naja nigricollis Venom on the Production of Methaemoglobin

open access: yesToxins, 2018
Snakebite envenomation is an affliction currently estimated to be killing upwards of 100,000 people annually. Snakebite is associated with a diverse pathophysiology due to the magnitude of variation in venom composition that is observed worldwide.
Harry F. Williams   +9 more
doaj   +1 more source

Development of a high-throughput in vitro screening method for the assessment of cell-damaging activities of snake venoms.

open access: yesPLoS Neglected Tropical Diseases, 2023
Snakebite envenoming is a globally important public health issue that has devastating consequences on human health and well-being, with annual mortality rates between 81,000 and 138,000.
Matyas A Bittenbinder   +8 more
doaj   +1 more source

From VIPERS to SDSS: Unveiling galaxy spectra evolution over 9 Gyr through unsupervised machine-learning [PDF]

open access: yesA&A 687, A76 (2024)
Aims: This study aims to trace the chronological evolution of galaxy spectra over cosmic time. Focusing on the VIPERS dataset, we seek to understand the diverse population of galaxies within narrow redshift bins, comparing our findings with the previously mapped diversity of SDSS galaxies.
arxiv   +1 more source

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