Results 101 to 110 of about 1,959,636 (236)
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
, 2011 Amsacta moorei Entomopoxvirüs (AmEV) Poxviridae familyasına ve Entomopoxviridae subfamilyasına ait bir böcek virüsüdür. AmEV `nin tüm genom analizinin yapıldığı çalışmada AMV133 kodlu açık okuma zincirinin muhtemel bir lipaz kodladığı ileri sürülmüştür ...
İnci Cevher
core
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
, 2013 Nakil sonrası dönemde malign hastalık gelişmesi organ naklinin en önemli komplikasyonlarından biridir. Malign hastalık gelişmesinde; immünsüpressif ilaçlar, human herpes virüs 8, Ebstein Barr virüs gibi viral enfeksiyonlar, güneşe maruz kalma ve kişiye ...
Arbil Açıkalın +6 more
core +1 more source
Ankara Sağlık Bilimleri Dergisi, 2019 Amaç: Araştırmanın amacı sağlık yüksekokulu öğrencilerinin HPV enfeksiyonu ve HPV aşısı ile ilgili bilgi ve görüşlerinin belirlenmesidir. Yöntem: Araştırma tanımlayıcı tiptedir.
Mükerrem Başli +2 more
doaj
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
, 2012 Özet: Bu çalışma Eskişehir ili şeker pancarı yetiştiriciliği yapılan alanlarda sorun olan virüs hastalıklarının belirlenmesi amacıyla gerçekleştirilmiştir.
Nejla YARDIMCI +2 more
core +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source