Results 81 to 90 of about 10,523,720 (359)

Correction: Guo et al. A Mixture of T-Cell Epitope Peptides Derived from Human Respiratory Syncytial Virus F Protein Conferred Protection in DR1-TCR Tg Mice. Vaccines 2024, 12, 77

open access: yesVaccines
The authors would like to make the following corrections to this published paper [...]
Hong Guo   +9 more
doaj   +1 more source

A rapid and sensitive recombinase aided amplification assay to detect hepatitis B virus without DNA extraction

open access: yesBMC Infectious Diseases, 2019
Background Hepatitis B virus (HBV) infection is the major public health problem worldwide. In clinical practice, serological and molecular assays are the most commonly used diagnostic methods to detect HBV infection in clinical practices. Methods Here we
Xin-xin Shen   +10 more
doaj   +1 more source

Viral vectored vaccines: design, development, preventive and therapeutic applications in human diseases

open access: yesSignal Transduction and Targeted Therapy, 2023
Human diseases, particularly infectious diseases and cancers, pose unprecedented challenges to public health security and the global economy.
Shen Wang   +9 more
semanticscholar   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Aetiological Characteristics of Infectious Diarrhea in Yantai City, Shandong Province, China in 2017

open access: yesViruses, 2022
This study aimed to analyse the pathogenic spectrum and epidemiological characteristics of infectious diarrhea in Yantai City, Shandong Province, China and provide a reference for its prevention and control.
Zhenlu Sun   +8 more
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Meta-analysis of gene expression profiles in long-term non-progressors infected with HIV-1

open access: yesBMC Medical Genomics, 2019
Background In the absence of antiretroviral treatments (ARTs), a small group of individuals infected with HIV, including long-term non-progressors (LTNPs) who maintain high levels of CD4+ T cells for more than 7–10 years in the absence of ART and in ...
Sun Young Lee   +4 more
doaj   +1 more source

Epidemiological characteristics of seven notifiable respiratory infectious diseases in the mainland of China: an analysis of national surveillance data from 2017 to 2021

open access: yesInfectious Diseases of Poverty, 2023
Background Respiratory infectious diseases (RIDs) remain a pressing public health concern, posing a significant threat to the well-being and lives of individuals.
Le-le Deng   +6 more
doaj   +1 more source

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

open access: yesFEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen   +2 more
wiley   +1 more source

Reduction in morbidity and mortality from childhood diarrhoeal disease after species A rotavirus vaccine introduction in Latin America : a review

open access: yesMemorias do Instituto Oswaldo Cruz, 2011
Countries in Latin America were among the first to implement routine vaccination against species A rotavirus (RVA). We evaluate data from Latin America on reductions in gastroenteritis and RVA disease burden following the introduction of RVA vaccine ...
Rishi Desai   +5 more
doaj   +1 more source

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