Results 1 to 10 of about 70,776 (216)

Flaviviruses in AntiTumor Therapy

Viruses, 2023
Oncolytic viruses offer a promising approach to tumor treatment. These viruses not only have a direct lytic effect on tumor cells but can also modify the tumor microenvironment and activate antitumor immunity.
Alina S. Nazarenko, Mikhail F. Vorovitch, Yulia K. Biryukova, Nikolay B. Pestov, Ekaterina A. Orlova, Nickolai A. Barlev, Nadezhda M. Kolyasnikova, Aydar A. Ishmukhametov   +7 more
doaj   +1 more source

Early Permissiveness of Central Nervous System Cells to Measles Virus Infection Is Determined by Hyperfusogenicity and Interferon Pressure

Viruses, 2023
The cessation of measles virus (MeV) vaccination in more than 40 countries as a consequence of the COVID-19 pandemic is expected to significantly increase deaths due to measles.
Marion Ferren, Alexandre Lalande, Mathieu Iampietro, Lola Canus, Didier Decimo, Denis Gerlier, Matteo Porotto, Cyrille Mathieu   +7 more
doaj   +1 more source

Surveillance of West Nile virus infection in Kashgar Region, Xinjiang, China, 2013–2016

Scientific Reports, 2021
West Nile virus (WNV) was first isolated in mainland China from mosquitoes in Jiashi County, Kashgar Region, Xinjiang in 2011, following local outbreaks of viral meningitis and encephalitis caused by WNV.
Yanping Zhang, Wenwen Lei, Yali Wang, Haitian Sui, Bo Liu, Fan Li, Ying He, Zhaoxia Li, Shihong Fu, Lu Wang, Limin Xu, Muti Mahe, Zhenguo Gao, Tuerxun Mamutijiang, Zhi Lv, Nijuan Xiang, Lei Zhou, Daxin Ni, Guodong Liang, Qun Li, Huanyu Wang, Zijian Feng   +21 more
doaj   +1 more source

Environmental factors and spatiotemporal distribution of Japanese encephalitis after vaccination campaign in Guizhou Province, China (2004–2016)

BMC Infectious Diseases, 2021
Background Although a vaccination campaign has been conducted since 2004, Japanese encephalitis (JE) is still a public health problem in Guizhou, one of the provinces with the highest incidence of JE in China.
Suye Zhao, Yidan Li, Shihong Fu, Ming Liu, Fan Li, Chunting Liu, Jing Yu, Liping Rui, Dingming Wang, Huanyu Wang   +9 more
doaj   +1 more source

Older patients with COVID‐19 and neuropsychiatric conditions: A study of risk factors for mortality

Brain and Behavior, Volume 12, Issue 12, December 2022., 2022
Abstract Background Little is known about risk factors for mortality in older patients with COVID‐19 and neuropsychiatric conditions. Methods We conducted a multicentric retrospective observational study at Assistance Publique‐Hôpitaux de Paris. We selected inpatients aged 70 years or older, with COVID‐19 and preexisting neuropsychiatric comorbidities
Vi‐Huong Nguyen‐Michel, Marion Houot, Cécile Delorme, Aude Sangaré, Ana Gales, Valerio Frazzini, Aurélie Hanin, Djamal Aissani, Thanh Trân, Bruno Oquendo, Flora Ketz, Carmelo Lafuente‐Lafuente, Christel Oasi, Kiyoka Kinugawa, Gaëlle Ouvrard, Renata Ursu, Bertrand Degos, Benjamin Rohaut, Sophie Demeret, Virginie Lambrecq, Vincent Navarro, Emmanuel Fournier, Jean‐Christophe Corvol, Alaina Borden   +23 more
wiley   +1 more source

Special Issue: “Viral Genetic Diversity”

Viruses, 2022
Some say that small is beautiful, and if beauty could be measured by levels of diversity and complexity, we could definitely say that viruses are beautiful [...]
Jean-Michel Heraud, Anne Lavergne, Richard Njouom   +2 more
doaj   +1 more source

Host–Pathogen Interactions Influencing Zoonotic Spillover Potential and Transmission in Humans

Viruses, 2023
Emerging infectious diseases of zoonotic origin are an ever-increasing public health risk and economic burden. The factors that determine if and when an animal virus is able to spill over into the human population with sufficient success to achieve ...
Beatriz Escudero-Pérez, Alexandre Lalande, Cyrille Mathieu, Philip Lawrence   +3 more
doaj   +1 more source

Regulatory T cell‐derived interleukin‐15 promotes the diversity of immunological memory

European Journal of Immunology, Volume 53, Issue 1, January 2023., 2023
We investigated the identity of IL‐15 producing cells using several mouse strains with cell type‐specific loss of IL‐15 expression. After the resolution of acute infection, IL‐15 secreted by regulatory cells, but not skeletal muscles or myeloid cells, was required for the maintenance of a subset of memory cells referred to as terminal effector memory T
Alaa Madi, Jingxia Wu, Sicong Ma, Nina Weisshaar, Alessa Mieg, Marvin Hering, Yanan Ming, Ferdinand Zettl, Kerstin Mohr, Nora ten Bosch, Tilo Schlimbach, Franziska Hertel, Guoliang Cui   +12 more
wiley   +1 more source

A companion to the preclinical common data elements for rodent models of pediatric acquired epilepsy: A report of the TASK3‐WG1B, Pediatric and Genetic Models Working Group of the ILAE/AES Joint Translational Task Force

Epilepsia Open, EarlyView., 2022
Abstract Epilepsy syndromes during the early years of life may be attributed to an acquired insult, such as hypoxic–ischemic injury, infection, status epilepticus, or brain trauma. These conditions are frequently modeled in experimental rodents to delineate mechanisms of epileptogenesis and investigate novel therapeutic strategies.
Anna‐Maria Katsarou, Hana Kubova, Stéphane Auvin, Massimo Mantegazza, Melissa Barker‐Haliski, Aristea S. Galanopoulou, Christopher A. Reid, Bridgette D. Semple   +7 more
wiley   +1 more source

A companion to the preclinical common data elements for phenotyping seizures and epilepsy in rodent models. A report of the TASK3‐WG1C: Phenotyping working group of the ILAE/AES joint translational task force

Epilepsia Open, EarlyView., 2022
Abstract Epilepsy is a heterogeneous disorder characterized by spontaneous seizures and behavioral comorbidities. The underlying mechanisms of seizures and epilepsy across various syndromes lead to diverse clinical presentation and features. Similarly, animal models of epilepsy arise from numerous dissimilar inciting events.
Melissa Barker‐Haliski, Julika Pitsch, Aristea S. Galanopoulou, Rüdiger Köhling   +3 more
wiley   +1 more source