Results 191 to 200 of about 663,857 (285)

Comprehensive Viral Detection and Profiling of Plasma Cell‐Free RNA in Patients With Suspected Hemophagocytic Lymphohistiocytosis

Journal of Medical Virology, Volume 98, Issue 9, September 2026.
ABSTRACT Hemophagocytic lymphohistiocytosis (HLH) is a severe, rapidly progressive disease. While viral infection is considered a common etiology of pediatric HLH, specific causative viruses other than the Epstein‐Barr virus (EBV) have been rarely identified.
Yuto Fukuda, Kazuhiro Horiba, Masanori Hashino, Shinji Kawabe, Hiroki Miura, Yoshiki Kawamura, Makito Tanaka, Takako Suzuki, Yuka Torii, Hideki Muramatsu, Yoshiyuki Takahashi, Tetsushi Yoshikawa, Jun‐ichi Kawada   +12 more
wiley   +1 more source

Revisiting Acyclovir Dosing for Adult Viral Encephalitis Using a Full Bayesian LeiCNS PBPK Modeling Approach. [PDF]

Clin Pharmacokinet
Sun M, Manson ML, Märtson AG, Bodilsen J, de Lange ECM, Guo T.   +5 more
europepmc   +1 more source

Admission‐Time Clinicolaboratory Phenotypes for Early Differentiation of Severe Fever With Thrombocytopenia Syndrome and Hemorrhagic Fever With Renal Syndrome

Journal of Medical Virology, Volume 98, Issue 9, September 2026.
ABSTRACT Early differentiation of severe fever with thrombocytopenia syndrome (SFTS) and hemorrhagic fever with renal syndrome (HFRS) remains difficult in endemic settings. In this single‐center retrospective comparative study, we analyzed admission‐time demographic, clinical, and laboratory data from 330 hospitalized patients with laboratory‐confirmed
Ruize Ma, Yanli Xu, Shuwen Ding, Ruihua Zhang, Jingxia Wang, Zhouling Jiang, Ling Lin, Zhihai Chen   +7 more
wiley   +1 more source

Chandipura Virus Causing Large Viral Encephalitis Outbreaks in India. [PDF]

Pathogens
Brisse ME, Ly H.
europepmc   +1 more source

Eugenol‐Derived Piperazine Mannich Bases as Selective Inhibitors of Mayaro Virus: In Vitro Antiviral Evaluation and Mechanistic Insights

Journal of Medical Virology, Volume 98, Issue 9, September 2026.
ABSTRACT Arboviruses represent an ongoing global health challenge, particularly in tropical regions where diseases caused by Chikungunya virus (CHIKV) and Mayaro virus (MAYV) continue to emerge. Given the absence of licensed antiviral therapies, the identification of effective small molecules remains critical.
Adriana Cotta Cardoso Reis, Amália Luíza de Sousa da Silva, Camila Portruneli, Augusto Vieira Pontes Silva, Saulo Fehelberg Pinto Braga, Igor Rodrigues Lapa, Thiago Belarmino de Souza, Lucas Lopardi Franco, Diogo Teixeira Carvalho, Geraldo Célio Brandão   +9 more
wiley   +1 more source

Development of a prediction model integrating PD-1 and ICOS for early differential diagnosis between autoimmune and viral encephalitis. [PDF]

Front Immunol
Xu K, Jia J, Duan Y, Chen S, Xiao X, Zhu F, Wang X, Gu Y, Tian J, Xue Q.   +9 more
europepmc   +1 more source

DAMPs, PAMPs, and Alarmins: From Mechanism to Therapy

MedComm, Volume 7, Issue 9, September 2026.
This review synthesizes the expanding biology of PAMPs and DAMPs, from their molecular sources and sensing mechanisms to regulatory networks that govern inflammation and homeostasis. Spanning from classical immune activation to trained immunity and interorgan communication, we highlight the interplay between PAMPs and DAMPs and their context‐dependent ...
Xuanxuan Yu, Yuqin Jin, Baochao Li, Jie Deng, Yiwen Zhou, Jinglun Zhang, Huang Li   +6 more
wiley   +1 more source

A Dual Diagnostic Dilemma: Viral Encephalitis and Cerebral Venous Thrombosis. [PDF]

Cureus
Khan A, Khan MHUH, Khan SU, Hayat K, Khan A, Arsalan M, Mushtaq MH, Sarfaraz H, Abbas M.   +8 more
europepmc   +1 more source

Role of Tertiary Lymphoid Structures in Autoimmune Diseases and Cancer

MedComm, Volume 7, Issue 9, September 2026.
Schematic overview of tertiary lymphoid structures (TLSs): The development process, detection, and the immune function that depends on the environment in different disease contexts of TLS. TLSs originate from loose lymphoid aggregates that acquire ordered follicular architecture to become primary follicular‐like TLS, before maturing into ...
Ze Yan, Bin Wen, Ying Hu, Xiaocui Wang, Xuemei Duan, Haonan Li, Shumin Dong, Yufeng Fan, Caihong Wang, Shutong Yang, Huifeng Shang, Yukai Jing   +11 more
wiley   +1 more source

Development of a Gold Nanoparticle‐Assisted Multiplex Polymerase Chain Reaction Assay for Selected Hospital‐Acquired Infections‐Associated Bacterial and Fungal Pathogens

ChemistryOpen, Volume 15, Issue 9, September 2026.
Gold nanoparticle‐assisted multiplex PCR enables the simultaneous detection of six major hospital‐acquired infection‐associated pathogens by improving amplification performance and assay specificity, providing an analytical proof‐of‐concept for rapid molecular identification.
Kubra Aslan, Emre Erden Kopar, Serap Evran   +2 more
wiley   +1 more source