Results 131 to 140 of about 2,147,758 (302)
Putting viral hepatitis on the map [PDF]
The DVH-funded FOA PS08-801 was intended to integrate primary and secondary viral hepatitis prevention services, education and counseling into health care settings and programs that serve adults at risk for viral hepatitis.
core
Versatile vector tools for efficient protein screening across multiple expression systems
FEBS Open Bio, EarlyView.A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source
Viral entry mechanisms: the role of molecular simulation in unlocking a key step in viral infections
FEBS Open BioViral infections are a major global health concern, affecting millions of people each year. Viral entry is one of the crucial stages in the infection process, but its details remain elusive. Enveloped viruses are enclosed by a lipid membrane that protects their genetic material and these viruses are linked to various human illnesses, including ...
Valério, Mariana +4 more
openaire +4 more sources
Small RNA pathways in mammalian oocytes
FEBS Open Bio, EarlyView.Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
Viral hepatitis surveillance United States, 2012 [PDF]
As part of CDC\ue2\u20ac\u2122s National Notifiable Disease Surveillance System (NNDSS), viral hepatitis case-reports are received electronically from state health departments via CDC\ue2\u20ac\u2122s National Electronic Telecommunications System for ...
core
Development of SARS-CoV-2 entry antivirals
Cell InsightThe global outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) threatened human health and public safety. The development of anti-SARS-CoV-2 therapies have been essential to curb the spread of SARS-CoV-2. Particularly, antivirals
Meiyue Dong +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Simulation results for different viral entry points.
, 2015 Simulation results of cellular space fraction, Sc, for DSP and tongue over a 48 hour timescale for maximal replication rate, ξ, and rate of FMDV resource consumption, ρ, both set at 0.29 × their default estimates.
Kyriaki Giorgakoudi (802788) +5 more
core +1 more source
Characterization of Viral Entry Inhibitors
, 2014 Hepatitis C virus (HCV), Human Immunodeficiency virus (HIV) and Herpes Simplex virus (HSV) are pathogenic viruses known to cause liver disorder, acquired immunodeficiency and skin lesions, respectively.
Chamoun Emanuelli, Ana M
core +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source