Results 161 to 170 of about 3,800,153 (377)

Collaboration Between Host and Viral Factors Shape SARS-CoV-2 Evolution [PDF]

, 2021
Connor Bamford, Lindsay Broadbent, Elihú Aranday-Cortés, Mary McCabe, James McKenna, David Courtney, Olivier Touzelet, Ahlam Ali, Grace Roberts, Guillermo López–Campos, David Simpson, Conall McCaughey, Derek Fairley, Ken Mills, Ultan F. Power, the Breathing Together Investigators   +15 more
openalex   +1 more source

Author Correction: Intradermal needle-free injection prevents African Swine Fever transmission, while intramuscular needle injection does not

Scientific Reports, 2023
Muhammad Salman, Hongyao Lin, Roypim Suntisukwattana, Parin Watcharavongtip, Patumporn Jermsutjarit, Angkana Tantituvanont, Dachrit Nilubol   +6 more
doaj   +1 more source

Influenza Hemagglutinin and Neuraminidase: Yin–Yang Proteins Coevolving to Thwart Immunity

Viruses, 2019
Influenza A virions possess two surface glycoproteins—the hemagglutinin (HA) and neuraminidase (NA)—which exert opposite functions. HA attaches virions to cells by binding to terminal sialic acid residues on glycoproteins/glycolipids to ...
Ivan Kosik, Jonathan W. Yewdell
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Pathology and viral metagenomics, a recent history [PDF]

, 2013
Human, animal and plant viral pathologies have greatly benefited from recent metagenomics development. Viral metagenomics is a culture-independent approach used to investigate the complete viral genetic populations of a sample.
Albina, Emmanuel, Bernardo, Pauline, Eloit, Marc, Fernandez, Emmanuel, Filloux, Denis, Roumagnac, Philippe   +5 more
core  

Giant Viruses—Big Surprises

Viruses, 2019
Viruses are the most prevalent infectious agents, populating almost every ecosystem on earth. Most viruses carry only a handful of genes supporting their replication and the production of capsids.
Nadav Brandes, Michal Linial
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Host-Parasite Co-evolution and Optimal Mutation Rates for Semi-conservative Quasispecies

, 2004
In this paper, we extend a model of host-parasite co-evolution to incorporate the semi-conservative nature of DNA replication for both the host and the parasite.
D. Voet, J. W. Drake, M. Eigen, M. Eigen, P. Schuster   +4 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Low Postseroconversion CD4⁺ T-cell Level Is Associated with Faster Disease Progression and Higher Viral Evolutionary Rate in HIV-2 Infection

mBio, 2019
A positive correlation between virus evolutionary rate and disease progression has been shown for human immunodeficiency virus type 1 (HIV-1) infection. Much less is known about HIV-2, the second causative agent of AIDS.
Angelica A. Palm, Philippe Lemey, Marianne Jansson, Fredrik Månsson, Anders Kvist, Zsófia Szojka, Antonio Biague, Zacarias José da Silva, Sarah L. Rowland-Jones, Hans Norrgren, Joakim Esbjörnsson, Patrik Medstrand   +11 more
doaj   +1 more source