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Evolution of a viral nucleocapid
Nature Reviews Microbiology, 2021This study reports the evolution of a bacterial enzyme that does not have an inherent RNA-binding activity into a virus-like nucleocapsid protein that efficiently packages and encapsidates copies of its own mRNA.
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Journal of Molecular Evolution, 1997
In studying population data, it is common to have many equally possible parsimonious trees. This has caused representational problems, all of which have been addressed by using various kinds of consensus trees. Recognizing that the incubus may in fact be the constraint of having to have a tree representation, several authors have investigated networks ...
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In studying population data, it is common to have many equally possible parsimonious trees. This has caused representational problems, all of which have been addressed by using various kinds of consensus trees. Recognizing that the incubus may in fact be the constraint of having to have a tree representation, several authors have investigated networks ...
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2009
Recent progress in comparative genomic and structural biology of microbial viruses, together with the discovery of unusual viruses in archaea and a giant virus in eukarya, has rejuvenated discussion on the origin of viruses. Many scientists now believe that viruses predated the Last Universal Common Ancestor (LUCA).
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Recent progress in comparative genomic and structural biology of microbial viruses, together with the discovery of unusual viruses in archaea and a giant virus in eukarya, has rejuvenated discussion on the origin of viruses. Many scientists now believe that viruses predated the Last Universal Common Ancestor (LUCA).
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Viral Persistence: Evolution of Viral Populations
1980There is an extensive literature dealing with persistent infections established by a wide variety of animal viruses. Several mechanisms have been suggested that may be involved in the establishment and maintenance of persistent infection by a normally virulent, cytolytic virus.
Julius S. Youngner, Olivia T. Preble
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Cooperation: another mechanism of viral evolution
Trends in Microbiology, 2013RNA viruses evolve rapidly under selection pressure as a result of the high error rates of viral RNA polymerase. 'Cooperation' between wild type and variant measles virus (MV) genomes through the heterooligomer formation of a viral protein has recently been shown to act as a mechanism of viral evolution.
Yuta, Shirogane +2 more
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SARS-CoV-2 viral clearance and evolution varies by type and severity of immunodeficiency
Science Translational MedicineDespite vaccination and antiviral therapies, immunocompromised individuals are at risk for prolonged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, but the immune defects that predispose an individual to persistent coronavirus ...
Yijia Li +32 more
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Viral evolution: beyond drift and shift
Current Opinion in Microbiology, 2015Technological advances have allowed aspects of viral evolution to be explored at unprecedented scales. As a consequence, new quantitative approaches are needed to investigate features of viral evolution that fall outside traditional areas of study, such as antigenic evolution.
Benjamin D, Greenbaum, Elodie, Ghedin
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Evolution of viral DNA-dependent RNA polymerases
Virus Genes, 1995The DNA-dependent RNA polymerase (DdRP or RNAP) is an essential enzyme of transcription of replicating systems of prokaryotic and eukaryotic organisms as well as cytoplasmic DNA viruses. DdRPs are complex multisubunit enzymes consisting of 8-14 subunits, including two large subunits and several smaller polypeptides (small subunits). An extensive search
K C, Sonntag, G, Darai
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Beyond Omicron: what’s next for COVID’s viral evolution
Nature, 2021E. Callaway
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